Machine Learning-Based Analysis Reveals Triterpene Saponins and Their Aglycones in Cimicifuga racemosa as Critical Mediators of AMPK Activation [PDF]
PharmaceuticsCimicifuga racemosa (CR) extracts contain diverse constituents such as saponins. These saponins, which act as a defense against herbivores and pathogens also show promise in treating human conditions such as heart failure, pain, hypercholesterolemia ...
Jürgen Drewe +4 more
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AMPK Activation by Cimicifuga racemosa Extract Ze 450 Is Associated with Metabolic Effects and Cellular Resilience against Age-Related Pathologies in Different Tissue Cell Types [PDF]
PharmaceuticsCimicifuga racemosa extracts (CREs) have gained well-established use for the treatment of menopausal symptoms such as hot flushes and excessive sweating, and weight gain.
Madeline Günther +8 more
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Effect of Cimicifuga racemosa on metabolic parameters in women with menopausal symptoms. A retrospective observational study (CIMBOLIC) [PDF]
Репродуктивная эндокринология, 2020 Purpose. To compare the influence of Cimicifuga racemosa extract (CR, Ze 450) and menopausal hormone therapy (MHT) on metabolic parameters and body weight in symptomatic menopausal women. Methods.
L. Friederichsen +8 more
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Does Cimicifuga racemosa have the effects like estrogen on the sublingual gland in ovariectomized rats? [PDF]
Biological Research, 2017 Background Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen.
Yun‑Meng Da +7 more
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Bridging Pharmacopeial Standards and Chemical Reality of Triterpene Glycosides in Actaea racemosa [PDF]
PlantsActaea racemosa L. (syn. Cimicifuga racemosa (L.) Nutt., black cohosh) rhizomes contain triterpene glycosides (TTGs) that serve as principal quality markers in the European Pharmacopoeia (Ph. Eur.) monograph.
Larisa-Mălina Cătăuță +5 more
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Determination of caffeic acid in root and rhizome of Black cohosh (Cimicifuga racemosa (L.) Nutt.) [PDF]
Current Issues in Pharmacy and Medical Sciences, 2014 Cimicifuga racemosa, is a plant with a diverse and long history of medicinal use. Caffeic acid, bioactive compound, which often occurs with other polyphenols can influence the biological activity of this plant.
Zapala Karolina +2 more
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Exploring the Efficacy and Safety of Black Cohosh (Cimicifuga racemosa) in Menopausal Symptom Management [PDF]
Journal of Mid-Life HealthBlack cohosh (Cimicifuga racemosa) is a perennial plant used to treat menopause. This plant is known to have a serotonergic rather than estrogenic impact. It has been recommended to treat vasomotor symptoms associated with breast cancer patients. It also
Kritiksha Hedaoo +4 more
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Cimicifuga racemosa: terapia alternativa para o climatério / Cimicifuga racemosa: alternative therapy for climacteric [PDF]
Brazilian Journal of Development, 2022 O artigo correlaciona a fitoterapia com a saúde da mulher, objetivando esclarecer os benefícios e a importância dessa terapia alternativa, especialmente durante o climatério. Nesse caso, o enfoque foi o uso da Cimicifuga racemosa para alívio dessas manifestações, como os fogachos, previamente submetidas à análise médica.
Sabrina Jéssica Pedrosa Ribeiro +7 more
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E ffect of Black Cohosh (Cimicifuga Racemosa) on Vasomotor Symptoms in Postmenopausal Women: A Randomized Clinical Trial [PDF]
Journal of Caring Sciences, 2013 Introduction:Hot flash is considered to be an early and common symptom of menopause. The present study aimed to determine the impact of black cohosh (Cimicifuga racemosa) on vasomotor symptoms in postmenopausal women.
Mahnaz Shahnazi +3 more
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Chlorination diversifies Cimicifuga racemosa triterpene glycosides. [PDF]
J Nat Prod, 2007 Extracts from the roots and rhizomes of black cohosh (Cimicifuga racemosa) are widely used as dietary supplements to alleviate menopausal symptoms. State-of-the-art quality control measures involve phytochemical fingerprinting of the triterpene glycosides for species identification and chemical standardization by HPLC.
Chen SN +9 more
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