AMPK Activation by Cimicifuga racemosa Extract Ze 450 Is Associated with Metabolic Effects and Cellular Resilience against Age-Related Pathologies in Different Tissue Cell Types [PDF]
PharmaceuticsCimicifuga racemosa extracts (CREs) have gained well-established use for the treatment of menopausal symptoms such as hot flushes and excessive sweating, and weight gain.
Madeline Günther +8 more
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Effect of Cimicifuga racemosa on metabolic parameters in women with menopausal symptoms. A retrospective observational study (CIMBOLIC) [PDF]
Репродуктивная эндокринология, 2020 Purpose. To compare the influence of Cimicifuga racemosa extract (CR, Ze 450) and menopausal hormone therapy (MHT) on metabolic parameters and body weight in symptomatic menopausal women. Methods.
L. Friederichsen +8 more
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Does Cimicifuga racemosa have the effects like estrogen on the sublingual gland in ovariectomized rats? [PDF]
Biological Research, 2017 Background Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen.
Yun‑Meng Da +7 more
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Exploring the Efficacy and Safety of Black Cohosh (Cimicifuga racemosa) in Menopausal Symptom Management [PDF]
Journal of Mid-Life HealthBlack cohosh (Cimicifuga racemosa) is a perennial plant used to treat menopause. This plant is known to have a serotonergic rather than estrogenic impact. It has been recommended to treat vasomotor symptoms associated with breast cancer patients. It also
Kritiksha Hedaoo +4 more
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Machine Learning-Based Analysis Reveals Triterpene Saponins and Their Aglycones in Cimicifuga racemosa as Critical Mediators of AMPK Activation [PDF]
PharmaceuticsCimicifuga racemosa (CR) extracts contain diverse constituents such as saponins. These saponins, which act as a defense against herbivores and pathogens also show promise in treating human conditions such as heart failure, pain, hypercholesterolemia ...
Jürgen Drewe +4 more
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E ffect of Black Cohosh (Cimicifuga Racemosa) on Vasomotor Symptoms in Postmenopausal Women: A Randomized Clinical Trial [PDF]
Journal of Caring Sciences, 2013 Introduction:Hot flash is considered to be an early and common symptom of menopause. The present study aimed to determine the impact of black cohosh (Cimicifuga racemosa) on vasomotor symptoms in postmenopausal women.
Mahnaz Shahnazi +3 more
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On the Biosynthesis of Bioactive Tryptamines in Black Cohosh (Actaea racemosa L.) [PDF]
PlantsBotanical dietary supplements are widely used, but issues of authenticity, consistency, safety, and efficacy that complicate their poorly understood mechanism of action have prompted questions and concerns in the popular and scientific literature.
Martin J. Spiering +2 more
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Chlorination diversifies Cimicifuga racemosa triterpene glycosides. [PDF]
J Nat Prod, 2007 Extracts from the roots and rhizomes of black cohosh (Cimicifuga racemosa) are widely used as dietary supplements to alleviate menopausal symptoms. State-of-the-art quality control measures involve phytochemical fingerprinting of the triterpene glycosides for species identification and chemical standardization by HPLC.
Chen SN +9 more
europepmc +4 more sources
Exploring the Benefits of Herbal Medicine Composite 5 (HRMC5) for Skin Health Enhancement [PDF]
Current Issues in Molecular BiologyThe skin, as the body’s largest organ, is vital for protecting against environmental stressors, regulating temperature, and preventing water loss. Here, we examined the potential of a mixture of five traditional Korean herbal extracts—Cimicifuga racemosa,
Rira Ha +6 more
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Molecular mechanisms for pharmacological effects of drugs based on Cimicifuga racemosa extracts [PDF]
Гинекология, 2018 An estrogen-like activity is considered to be the main mechanism of action for Cimicifuga extract. At the same time, results of modern studies of molecular composition together with modern fundamental data indicate such critical mechanisms of action as ...
O.A.Gromova +4 more
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