Results 111 to 120 of about 84,748 (209)

Unveiling the Power of Deuterium in Drug Discovery: A Comprehensive Overview

MedComm, Volume 7, Issue 6, June 2026.
The role of deuterium replacement in drug discovery, its progress, opportunities, and challenges. ABSTRACT Deuterium, the heavy isotope of hydrogen, has unfolded as a cornerstone in modern drug discovery due to its potential to influence metabolic stability and pharmacokinetic behavior.
Mukta Lele, Ajit Manchare, Swapnali Parit, Amol D. Gholap, Krishna Jadhav, Navnath Hatvate, Keshav Raj Paudel, Satish Rojekar   +7 more
wiley   +1 more source

The Role of Endothelial Activation and Stress Index (EASIX) for Predicting Contrast-Induced Nephropathy and In-Hospital Mortality in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. [PDF]

Diagnostics (Basel)
Karauzum K, Tanık VO, Tas A, Mirzamidinov D, Simsek U, Gencer E, Celik F, Badalova N, Buyukbas FC, Yilmaz I, Kahraman G, Sahin T, Ural E.   +12 more
europepmc   +1 more source

Integrative Proteogenomic Characterization of Left‐Sided and Right‐Sided Colorectal Cancer

MedComm, Volume 7, Issue 6, June 2026.
This study performed whole‐exome sequencing, proteomic, and phosphoproteomic analysis on 80 pairs of tumor tissues and matched normal adjacent tissues from colorectal cancer patients. The integrated proteogenomic study provides a comprehensive and nuanced understanding of the molecular heterogeneity between left‐ and right‐sided colorectal cancer ...
An Huang, Haopeng Hong, Yonghui Sun, Zhaoya Gao, Jingxuan Xu, Jiajia Chen, Yong Yang, Zhongyi Chen, Hebing Chen, Ming Li, Xiaodong Wang, Jin Gu   +11 more
wiley   +1 more source

Evaluation of agmatine efficacy in contrast-induced nephropathy: experimental evidence in rat model. [PDF]

Acta Cir Bras
Yeniçeri M, Baş S, Şenoymak MC, Salmanoğlu M, Tanoğlu A.   +4 more
europepmc   +1 more source

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu, Kaifeng Niu, Qingran Kong, Shaorong Gao   +3 more
wiley   +1 more source

Long-Term Risk of Residual or Recurrent CIN 2-3 After LLETZ in Immunosuppressed vs. Immunocompetent Women: A 20-Year Cohort Study. [PDF]

Cancers (Basel)
Molina-Hinojosa CL, Carreras-Collado R, Saumoy-Linares M, Peñafiel J, Heydari F, Martí JC, Fernández-Montolí ME.   +6 more
europepmc   +1 more source

Planetary Health Diet Adherence Improves Weight and Body Composition During Energy Restriction

Obesity, Volume 34, Issue 6, Page 1265-1276, June 2026.
ABSTRACT Objective Obesity management relies on energy restriction, yet the contribution of dietary quality to weight‐loss and body composition outcomes during hypocaloric interventions remains poorly characterized. This study evaluated whether adherence to the Planetary Health Diet (PHD), as a measure of diet quality, and its key components is ...
Paola Mogna‐Peláez, Naixin Zhang, Marta Guasch‐Ferré, Fermin I. Milagro, José I. Riezu‐Boj, José I. Herrero, Mariana Elorz, Alberto Benito‐Boillos, Ana Luz Tobaruela‐Resola, Amelia Marti Del Moral, Josep A. Tur, J. Alfredo Martínez, Itziar Abete, M. Ángeles Zulet   +13 more
wiley   +1 more source

Genome-Wide DNA Methylation Profiling Reveals Ancestry-Associated Epigenetic Reprogramming in Cervical Intraepithelial Neoplasia. [PDF]

Int J Mol Sci
Masoud M, Shastri C, Banerjee R, Dasgupta S, Chavarria-Bernal H, Singh KP, Pierce JY, Dasgupta S.   +7 more
europepmc   +1 more source

When invasions go unnoticed: Public perception of the freshwater jellyfish Craspedacusta sowerbii in Europe

People and Nature, Volume 8, Issue 6, Page 1957-1973, June 2026.
Abstract Biological invasions are a major driver of biodiversity loss, yet inconspicuous or “cryptic” species often escape detection and public awareness, limiting management responses. We investigated the freshwater jellyfish Craspedacusta sowerbii, likely native to China and now present on six continents, through a 22‐month multilingual online survey
Guillaume Marchessaux, Kristína Slovák Švolíková, Barbora Števove, Ali Serhan Tarkan, Daniela Giannetto, Cristina Preda, Belma Kalamujić Stroil, Maciej K. Mańko, András Abonyi, Álmos Becz, Massimo Morpurgo, Evgeny A. Pakhomov, Levan Mumladze, Mar Bosch‐Belmar, Aino Hosia, Patricia Ventura, Jamileh Javidpour, Florian Lüskow   +17 more
wiley   +1 more source

Integrated Analysis of lncRNA-miRNA-mRNA ceRNA Network and Identification of Hub lncRNAs in Molecular Subtypes of Gastric Cancer as Potential Prognostic Indicators. [PDF]

Bioinform Biol Insights
Goftari SN, Bahrami AR, Matin MM.
europepmc   +1 more source