Results 161 to 170 of about 84,748 (209)

Evaluating DNA methylation markers and extended HPV genotyping in first-void urine for detecting high-grade cervical lesions in HPV-positive women: a cross-sectional study. [PDF]

open access: yesBMC Med
Tranberg M   +12 more
europepmc   +1 more source

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis. [PDF]

open access: yesSci Adv
Beernaert B   +31 more
europepmc   +1 more source

HPV self-sampling and physician-collected sampling for detection of precancerous lesions of the cervix. [PDF]

open access: yesBioinformation
Ferdous J   +7 more
europepmc   +1 more source

Chromosomal Instability (CIN) Phenotype, CIN High or CIN Low, Predicts Survival for Colorectal Cancer

Journal of Clinical Oncology, 2012
Purpose To examine whether chromosomal instability (CIN) phenotype, determined by the severity of CIN, can predict survival for stages II and III colorectal cancer (CRC). Patients and Methods We determined microsatellite instability (MSI) and loss of heterozygosity (LOH) status in 1,103 patients (training [n = 845] and validation [n = 258] sets with ...
Toshiaki, Watanabe   +12 more
openaire   +2 more sources

Cancer: a CINful evolution

Current Opinion in Cell Biology, 2018
Pioneering studies described cancer as an evolutionary process and detailed its intratumor heterogeneity in patients' specimens. The development of unbiased single-cell sequencing technologies confirmed these early observations and neoplasms are now widely recognized as populations of genetically, chromosomally and epigenetically distinct cells in ...
Altea, Targa, Giulia, Rancati
openaire   +2 more sources

CIN-ful cancers

Cancer Chemotherapy and Pharmacology, 2004
Aneuploidy has long been recognized to be a cardinal feature of many neoplasias. However, the role of aneuploidy in tumorigenesis continues to be a matter of debate. We believe that aneuploidy in cancers is the result of chromosomal instability, a process in which dividing cancer cells segregate their chromosomes with decreased fidelity.
Harith, Rajagopalan, Christoph, Lengauer
openaire   +2 more sources

Hysterectomy for Treatment of CIN

Journal of Lower Genital Tract Disease, 2003
The objective of this investigation was to determine the percentage of microinvasive and invasive cancers found when CIN 3 was treated by hysterectomy. The postoperative histologic findings of all patients with CIN 3 treated by conization or hysterectomy were analyzed.
Vesna, Kesic   +5 more
openaire   +2 more sources

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