Evaluating DNA methylation markers and extended HPV genotyping in first-void urine for detecting high-grade cervical lesions in HPV-positive women: a cross-sectional study. [PDF]
Tranberg M +12 more
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A method of estimating cervical cancers prevented by the introduction of national screening in Ireland. [PDF]
Grimes DR, Brennan A, Walsh C.
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Serum lipoprotein(a) and risk of contrast-induced nephropathy in patients with type 2 diabetes mellitus. [PDF]
Ling Y, Chen Y, Yu X, Zhang X.
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Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis. [PDF]
Beernaert B +31 more
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HPV self-sampling and physician-collected sampling for detection of precancerous lesions of the cervix. [PDF]
Ferdous J +7 more
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The effect of estrogen and its receptors on the progression of cervical intraepithelial neoplasia in postmenopausal women through synergistic interaction with HPV. [PDF]
Liu H +6 more
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Purpose To examine whether chromosomal instability (CIN) phenotype, determined by the severity of CIN, can predict survival for stages II and III colorectal cancer (CRC). Patients and Methods We determined microsatellite instability (MSI) and loss of heterozygosity (LOH) status in 1,103 patients (training [n = 845] and validation [n = 258] sets with ...
Toshiaki, Watanabe +12 more
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Pioneering studies described cancer as an evolutionary process and detailed its intratumor heterogeneity in patients' specimens. The development of unbiased single-cell sequencing technologies confirmed these early observations and neoplasms are now widely recognized as populations of genetically, chromosomally and epigenetically distinct cells in ...
Altea, Targa, Giulia, Rancati
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Aneuploidy has long been recognized to be a cardinal feature of many neoplasias. However, the role of aneuploidy in tumorigenesis continues to be a matter of debate. We believe that aneuploidy in cancers is the result of chromosomal instability, a process in which dividing cancer cells segregate their chromosomes with decreased fidelity.
Harith, Rajagopalan, Christoph, Lengauer
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Hysterectomy for Treatment of CIN
Journal of Lower Genital Tract Disease, 2003The objective of this investigation was to determine the percentage of microinvasive and invasive cancers found when CIN 3 was treated by hysterectomy. The postoperative histologic findings of all patients with CIN 3 treated by conization or hysterectomy were analyzed.
Vesna, Kesic +5 more
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