Centrosome clustering and Cyclin D1 gene amplification in double minutes are common events in chromosomal unstable bladder tumors [PDF]
, 2010 Background: Aneuploidy, centrosome abnormalities and gene amplification are hallmarks of chromosome instability (CIN) in cancer. Yet there are no studies of the in vivo behavior of these phenomena within the same bladder tumor.
A Valent +50 more
core +5 more sources
Assessment of P53 BCL-2 and CD34 in premalignant and malignant cervical lesions [PDF]
Journal of Krishna Institute of Medical Sciences University, 2022 Background: Cancer cells are characterized by loss of tumor suppressor genes, evasion of apoptosis and an upregulation in angiogenesis. Cervical cancer is the second most prominent cancer amongst young women of reproductive age after breast cancer.
Ekundina Victor Olukayode +5 more
doaj
The management of cervical intra-epithelial neoplasia (CIN): Extensiveness and costs in The Netherlands [PDF]
, 1995 In order to provide greater insight into both the extensiveness and the medical costs of the diagnosis and treatment of screen-detected cervical intra-epithelial neoplasia (CIN) in general medical practice in The Netherlands, data from national ...
Ballegooijen, M. (Marjolein) van +2 more
core +1 more source
Репродуктивная эндокринология, 2021 This study evaluated the clinical performance of the cobas 4800 HPV Test (Roche Molecular Systems, Pleasanton, CA, USA) for high-risk human papillomavirus (HR-HPV) testing with individual HPV-16/HPV-18 genotyping in women 21 years or older with atypical ...
M.H. Stoler, T.C. Wright, Jr., A. Sharma
doaj +1 more source
Improving Electrical Fault Detection Using Multiple Classifier Systems
EnergiesMachine Learning-based fault detection approaches in energy systems have gained prominence for their superior performance. These automated approaches can assist operators by highlighting anomalies and faults, providing a robust framework for improving ...
José Oliveira +5 more
doaj +1 more source
Guest Editorial Foreword to the Special Issue of the XII Symposium on Virtual and Augmented Reality
Journal on Interactive Systems, 2011 Nenhum resumo ...
Judith Kelner, Luciano Pereira Soares
doaj +1 more source
Kinase-independent role of cyclin D1 in chromosomal instability and mammary tumorigenesis [PDF]
, 2015 Cyclin D1 is an important molecular driver of human breast cancer but better understanding of its oncogenic mechanisms is needed, especially to enhance efforts in targeted therapeutics.
Addya, Sankar +18 more
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A subset of MMR‐proficient colon cancers responds to neoadjuvant immunotherapy
Molecular Oncology, EarlyView.Tan et al. reveal that a distinct subset of early‐stage pMMR colon cancers can respond to neoadjuvant immunotherapy. In the NICHE‐2 trial, responders (26%) were characterized by chromosomal instability, TP53 mutations, and proliferative cell‐cycle programs, whereas nonresponders showed metabolic and stromal reprogramming with TGF‐β‐driven ...
Eleonora Piumatti +3 more
wiley +1 more source
Liinc em Revista, 2019 RESUMO A ciência contemporânea e seus fundamentos metodológicos têm sido impactados pelo fenômeno do big data, que proclama que na era dos dados medidos em petabytes, de supercomputadores e sofisticados algoritmos, o método científico está obsoleto e que
Luís Fernando Sayão +1 more
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Human Pappilomavirus Genotype in Cervical Tissue of Patients with Cervical Intraepithelial Neoplasia (CIN) 1, CIN 2, and CIN 3 [PDF]
, 2016 Objectives: to determine the genotype of HPV in patients with precancerous lesions of cervical tissue.Materials and Methods: An observational study with cross sectional study of patients paraffin block CIN1, CIN2, CIN3 was conducted in Dr Soetomo ...
Alia, R. (Rahmi) +4 more
core +1 more source