Results 41 to 50 of about 431,500 (263)

Loop electrosurgical excision procedure versus cryotherapy in the treatment of cervical intraepithelialneoplasia: A systematic review and meta-analysis of randomized controlled trials [PDF]

, 2018
AIM: Invasive cervical cancer is proceeded by a phase of preinvasive disease that is slow to progress and can be detected, treated, and collectively referred to as cervical intraepithelial neoplasia (CIN).
Arduino, Bruno, Borgo, Maria, D'Alessandro, Pietro, Di Cello, Annalisa, Saccone, Gabriele, Venturella, Roberta, Zullo, Fulvio   +6 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of inosine pranobex on p16, Ki-67 expression in patients with HPV-associated cervical intraepithelial neoplasia [PDF]

Гинекология, 2018
The aim of the study - to determine the dynamics of expression of р16, Ki-67 in patients with HPV-associated cervical intraepithelial neoplasia (CIN) in the complex treatment with inosine pranobex. Materials and methods.
T V Klinyshkova, O N Mironova
doaj   +1 more source

ОСОБЕННОСТИ ЛОКАЛЬНОГО ИММУННОГО ОТВЕТА И ИММУНОГИСТОХИМИЧЕСКИЕ МАРКЕРЫ ПРОГНОЗА ПРИ РАКЕ ШЕЙКИ МАТКИ

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2023
Согласно современным данным, рак шейки матки (РШМ) занимает одно из ведущих мест в структуре злокачественных новообразований у женщин Республики Беларусь и Российской Федерации, а также является четвертым по распространенности видом рака среди женщин во ...
О. В. Шиман, В. С. Алексинский   +1 more
doaj   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Kur’an’da ‘İns’ ve ‘Cin’ Kelimelerinin Birbirlerine Atfında Öncelik-Sonralık Üzerine Bir İnceleme

Marife Dini Araştırmalar Dergisi, 2020
İnsanlar ve cinler, bazı açılardan birbirlerinden üstün kılınmış olan varlıklardır. Yirmi üç yıllık bir süre içinde vahyedilen Kur’an’ın, sıkça bahsedilen iki kelimenin tertibini rastgele kullanması düşünülemez.
Muhammed Ersöz
doaj   +1 more source

Phosphoenolpyruvate carboxykinase maintains glycolysis-driven growth in Drosophila tumors [PDF]

, 2017
Published online: 14 September 2017Tumors frequently fail to pass on all their chromosomes correctly during cell division, and this chromosomal instability (CIN) causes irregular aneuploidy and oxidative stress in cancer cells.
Gregory, S., Hussain, R., Khan, M., Saint, R., Shaukat, Z.   +4 more
core   +3 more sources

Ultrafast Vertical Organic Electrochemical Transistors With Ion‐Permeable Conductive Polymer Top Electrodes

Advanced Materials, EarlyView.
Vertical organic electrochemical transistors (vOECTs) are limited in speed by ion‐impermeable metal electrodes that slow ion injection. Using ion‐permeable PBFDO top electrodes allows direct vertical ion injection into BBL channels, achieving high current densities (>400 A cm−2), large on/off ratios (>106), and ultrafast switching in 28 µs. This sets a
Han‐Yan Wu, Yingxue An, Luigi Fabiano, Qifan Li, Qingqing Wang, Feng Zhang, Wenlong Jin, Miao Xiong, Junpeng Ji, Ugo Bruno, Grzegorz Greczynski, Grazia Maria Lucia Messina, Xianjie Liu, Chi‐Yuan Yang, Simone Fabiano   +14 more
wiley   +1 more source

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Addressing the CQI feedback delay in 5G/6G networks via machine learning and evolutionary computing

Intelligent and Converged Networks, 2022
5G networks apply adaptive modulation and coding according to the channel condition reported by the user in order to keep the mobile communication quality. However, the delay incurred by the feedback may make the channel quality indicator (CQI) obsolete.
Andson Balieiro, Kelvin Dias, Paulo Guarda   +2 more
doaj   +1 more source