Results 111 to 120 of about 33,127 (238)

Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: Towards the development of potential dual action antimalarials [PDF]

, 2012
A series of cinnamic acid/4-aminoquinoline conjugates conceived to link, through a proper retro-enantio dipeptide, a heterocyclic core known to prevent hemozoin formation, to a trans-cinnamic acid motif capable of inhibiting enzyme catalytic Cys residues,
Bianca C Perez, Cada Teixeira, Jiri Gut, Jose R B Gomes, Marta Figueiras, Paula Gomes, Philip J Rosenthal   +6 more
core   +1 more source

Patch Testing in Individuals With Diabetes Using Medical Devices. Part 2—Contact Allergy to Medical Device Allergens and New Patch Test Recommendations

Contact Dermatitis, EarlyView.
This study aimed to describe the prevalence of contact allergy to allergens found in diabetes medical devices (MDs) among diabetes MD users and suggest an updated MD patch test series. Of the 204 diabetes MD users (114 with skin rash to diabetes MDs and 90 without), 16.2% were positive to allergens found in diabetes MDs, which underlines the urgent ...
Josefin Ulriksdotter, Martin Mowitz, Thanisorn Sukakul, Magnus Bruze, Nils Hamnerius, Cecilia Svedman   +5 more
wiley   +1 more source

Synthesis and Molecular Modeling of Antioxidant and Anti-Inflammatory Five-Membered Heterocycle–Cinnamic Acid Hybrids

Molecules
In this study, the design and synthesis of a novel series of cinnamic acid and 1,2,4-triazole hybrids were reported, aiming to enhance antioxidant and lipoxygenase inhibitory activities through pharmacophore combination. Cinnamic acid derivatives and 1,2,
Konstantinos Theodoridis, Eleftherios Charissopoulos, Dimitra Tsioumela, Eleni Pontiki   +3 more
doaj   +1 more source

Synthesis of Cinnamic Acid Derivatives [PDF]

Advances in Computer Science Research, 2017
Yuping Guo, Yuanbiao Tu, Lei Zhao
openaire   +1 more source

Deciphering the properties and reaction mechanism of anhydromevalonate phosphate decarboxylase, a prenylated flavin mononucleotide‐dependent enzyme in the archaeal mevalonate pathway

The FEBS Journal, EarlyView.
Characterization of anhydromevalonate phosphate decarboxylase, the UbiD‐family decarboxylase involved in the archaeal mevalonate pathway, was conducted. The enzyme is responsible for the biosynthesis of isoprenoids, such as archaeal membrane lipids, respiratory quinones, and dolichols.
Rino Ishikawa, Natsumi Matsushima, Soma Ishimine, Honoka Nakamoto, Hajime Hayakawa, Yoko Yasuno, Tetsuro Shinada, Hiroshi Kawaide, Tomokazu Ito, Hisashi Hemmi   +9 more
wiley   +1 more source

Towards an integrated molecular understanding of plant hormones

Journal of Integrative Plant Biology, EarlyView.
This review offers a comprehensive overview of the nine plant hormones, delving into their biosynthesis, transport, signaling and crosstalk mechanisms. Because the complexity of plant hormonal control goes beyond these core elements, additional specific features are discussed. Lastly, this review highlights how fundamental insights drive hormonal‐based
Louise Vilain, Marie‐Laure Fauconnier, Manon Genva   +2 more
wiley   +1 more source

Antioxidant fractions and phenolic constituents from leaves of Pluchea carolinensis and Pluchea rosea [PDF]

, 2014
peer reviewedAbstract: Objective: To evaluated the antioxidant potential of several polar fractions of P. carolinensis and P. rosea as well as pure chemicals, some of them quantified in both species by HPLC. Methods: The antioxidant potential of polar
Dommes, Jacques, Frederich, Michel, Kevers, Claire, Perera Cordoba, Wilmer Hervet, Wauters, Jean-Noël   +4 more
core   +1 more source

Coniferyl aldehyde from the phenylpropanoid pathway targets pyruvate kinase in Dactylobotrys graminicola to confer sheath rot resistance in hulless barley

Journal of Integrative Plant Biology, EarlyView.
Hulless barley resists the newly identified sheath rot disease caused by the necrotrophic fungal pathogen Dactylobotrys graminicola by releasing coniferyl aldehyde, a natural compound that disrupts energy production in the fungus. ABSTRACT Dactylobotrys graminicola (Dgr), a necrotrophic fungal pathogen, has recently been identified as the causative ...
Haowen Zheng, Liyifan Chen, Jianguo Wei, Yuandi Xu, Rangrang Chen, Yu Li, Yan Liu, Jiahui Yan, Lu Hou, Yiliang Chen, Zhensheng Kang, Haifeng Zhang, Qiang Yao   +12 more
wiley   +1 more source

Host‐Induced Silencing of Rhizoctonia Solani 5‐Enolpyruvylshikimate‐3‐Phosphate Synthase Impairs Its Virulence in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sheath blight disease of rice caused by the fungal pathogen R. solani AG1‐IA remains a big threat to rice production worldwide. A limited genetic variation in rice for tolerance to this pathogen and little success in understanding how it defeats host defence are major reasons behind it.
Vinod Kumar, Apoorva Prasad, Akshita Goel, Vijay Kumar Sharma, Jagjeet Singh Lore, Arun Kumar   +5 more
wiley   +1 more source

The Structure of Carboxyl Methyltransferase Provides Insights Into the Substrate Specificity and Divergent Evolution of Iridoid

Plant Biotechnology Journal, EarlyView.
ABSTRACT Iridoids constitute a prominent class of plant‐specialised metabolites, with carbocyclic iridoids (e.g., geniposide) and secoiridoids (e.g., loganin) diverging early in their biosynthetic pathways. This divergence is marked by substrate‐specific carboxyl methyltransferases—GjGAMT and CrLAMT—that catalyse the decisive methylation step in ...
Li Li, Zhiteng Luo, Zhaoyin He, Jie Tang, Wuke Wei, Ruoting Zhan, Huihao Zhou, Dongming Ma   +7 more
wiley   +1 more source