Results 51 to 60 of about 469 (131)

Comparison of the efficacy and safety of ciprofol and propofol in sedating patients in the operating room and outside the operating room: a meta-analysis and systematic review

BMC Anesthesiology
Background As a new type of intravenous anesthetic, ciprofol has the advantages of fast onset of action, fast recovery and high clearance rate. This study aimed to investigate the effectiveness and safety of ciprofol versus traditional propofol for ...
Yanni Yang, Zekun Lang, Xiumei Wang, Peining Yang, Ning Meng, Yang Xing, Yatao Liu   +6 more
doaj   +1 more source

Ciprofol Ameliorates Myocardial Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through Upregulating HIF-1α

Drug Design, Development and Therapy
Ciprofol is a novel intravenous anesthetic that has been increasingly used in clinical anesthesia and sedation. Studies suggested that ciprofol reduced oxidative stress and inflammatory responses to alleviate cerebral ischemia/reperfusion (I/R) injury, but whether ciprofol protects the heart against I/R injury and the mechanisms are unknown. Herein, we
Jun Ding, Bi-Ying Wang, Yu-Fan Yang, Ling-Yu Kuai, Jing-jie Wan, Mian Zhang, Hai-Yan Xia, Yao Wang, Zhong Zheng, Xiao-Wen Meng, Ke Peng, Fu-Hai Ji   +11 more
openaire   +2 more sources

Ciprofol: A Novel Medication from Development towards Clinical Use

Translational Perioperative and Pain Medicine, 2021
Wang Tingting, Yao Shanglong, Zhang Limin, Liu Yong   +3 more
openaire   +1 more source

Issue Information

CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 5, Page 687-690, May 2024.
wiley   +1 more source

Comparative efficacy and safety of ciprofol, propofol, and propofol and etomidate mixture, and ciprofol and etomidate mixture in patients undergoing painless gastroscopy: A randomized, double-blind controlled clinical trial

Medicine
Background: To compare the efficacy and safety of ciprofol, propofol, propofol and etomidate mixture or ciprofol and etomidate mixture in patients undergoing painless gastroscopic anesthesia, and to explore the optimal plan to relieve the patient’s discomfort.
Yanlong Liu, Yihong Qian, Lilan Zhang, Shanliang Guo, Longcheng Fan, Mingsheng Zhang, Zhongyu Liu   +6 more
openaire   +2 more sources

Efficacy and Safety of Ciprofol Versus Propofol as Anesthetic for Patients Undergoing Painless Colonoscopy

Pain and Therapy
Ciprofol is a novel propofol analogue with a characteristic of hemodynamic stability. At present, there is a lack of research comparing the hemodynamic stability of ciprofol and propofol during painless colonoscopy. In this study, we aim to test the hypothesis that ciprofol is superior to propofol in terms of hemodynamic stability for sedation ...
Ke Qiang He, Ting Ting Huang, Meng Yuan Tan, Chen Gao, Sheng Wang   +4 more
openaire   +3 more sources

Comparison of the ED50 of Ciprofol Combined With or Without Fentanyl for Laryngeal Mask Airway Insertion in Children: A Prospective, Randomized, Open-Label, Dose-Response Trial

Drug Design, Development and Therapy
Sicong Wang, Yan Li, Fang Chen, Hua-Cheng Liu, Lezhou Pan, Wangning Shangguan Department of Anesthesiology and Perioperative Medicine, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Key Laboratory of ...
Wang S, Li Y, Chen F, Liu HC, Pan L, Shangguan W   +5 more
doaj  

Effects of ciprofol infusion on hemodynamics during induction and maintenance of anesthesia and on postoperative recovery in patients undergoing thoracoscopic lobectomy: Study protocol for a randomized, controlled trial.

PLoS ONE
IntroductionCiprofol, a new candidate drug, is effective and safe for the maintenance of anesthesia in non-cardiothoracic and non-neurological elective surgery.
Na Guo, Jianqiao Cao, Mingjie Duan, Fei Zhou, Wei Wang, Lingling Xu, Chuansong Wei, Xiumei Song   +7 more
doaj   +1 more source

The effects of ciprofol on haemodynamics under general anaesthesia during thoracoscopic surgery: a randomised, double-blind, controlled trial

BMC Anesthesiology
Background Propofol, a widely administered sedative, is associated with potential hemodynamic instability during anaesthesia. Ciprofol introduces a cyclopropyl group to the chemical structure of propofol, forming an R-shaped hand structure and is ...
Lifang Lan, Jianping Liao, Liuying Qin, Xuemei Wang, Tan Qin, Yanhua Chen, Jingchen Liu   +6 more
doaj   +1 more source

The efficacy and safety of remimazolam besylate, ciprofol, and propofol during hysteroscopy

Frontiers in Pharmacology
ObjectiveRemimazolam besylate and Ciprofol are newer sedatives used in minor surgeries. Propofol is a classic drug mainly used for short surgeries. This trial was conducted to compare the efficacy and safety of remimazolam besylate, ciprofol, and propofol during hysteroscopic surgeries.MethodsPatients undergoing hysteroscopy were randomly assigned to ...
Weifeng Shan, Shuying Gao, Mengting Ai, Haiyan Lan, Gongchen Duan, Xiaoli Dong, Qiaomin Xu, Yini Wu, Jimin Wu   +8 more
openaire   +2 more sources