Advantages of Ciprofol with Special Consideration of Pediatric Anesthesia [PDF]
Children (Basel)The search for an ideal anesthetic has always been a major goal in anesthesiology. In recent years, the introduction of ciprofol has marked a major breakthrough in the pharmacological field, following the introduction of dexmedetomidine. Ciprofol has similar characteristics to propofol but with greater hemodynamic stability.
Vittori A +12 more
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Chinese Medical Journal, 2022 . Background:. Ciprofol (HSK3486; Haisco Pharmaceutical Group Co., Ltd., Chengdu, China), developed as a novel 2,6-disubstituted phenol derivative showed similar tolerability and efficacy characteristics as propofol when applicated as continuous ...
Yongjun Liu +11 more
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Effect of ciprofol on swallowing function in patients undergoing painless gastrointestinal endoscopy
Medicine, 2023 Background: Gastroscopy is one of the most commonly used diagnostic modalities for upper gastrointestinal disorders. This study compared the effect of ciprofol and propofol on swallowing function during painless gastroenteroscopy.
Jinsong Liao +6 more
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Safety and efficacy of esketamine combined with propofol or ciprofol sedation for electroconvulsive therapy in patients with major depressive disorder: protocol for a randomized, double-blind, controlled trial with factorial design [PDF]
IntroductionElectroconvulsive therapy (ECT) is one of the main strategies for major depressive disorder (MDD). Recently, the use of esketamine in the treatment of depression due to the rapid antidepressant effects has been highlighted.
De-zhen Su +10 more
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, 2023 Clinical and Translational Science, Volume 16, Issue 10, Page 1737-1740, October 2023.
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Efficacy and safety of ciprofol for sedation in outpatient gynecological procedures: a phase III multicenter randomized trial [PDF]
ObjectiveCiprofol (also known as cipepofol and HSK3486), is a compound similar to propofol in chemical structure and hypnotic effect. Herein we evaluated the efficacy and safety of ciprofol for sedation in outpatient gynecological procedures.MethodsThis ...
Dong-Xin Wang +11 more
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Pharmacological mechanism and clinical application of ciprofol
Frontiers in PharmacologyPropofol has become one of the most commonly used anesthetic agents because of its good sedative effects, rapid onset, and fast metabolism. However, its associated respiratory and circulatory depression and injection pain make it difficult for patients to tolerate.
Jianshun Zhou +10 more
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A bibliometric analysis of the published studies in ciprofol research
MedicineObjective: Ciprofol (HSK-3486), a novel intravenous anesthetic with structural similarities to propofol, has shown promising pharmacokinetic (PK) and pharmacodynamic (PD) profiles; however, clinical data regarding its efficacy and safety remain limited.
Wei Wu +3 more
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Immunity, Inflammation and Disease, Volume 13, Issue 7, July 2025.This study investigates the protective effects of ciprofol on hepatic ischemia/reperfusion (I/R) injury, demonstrating that it reduces inflammation and apoptosis in liver tissue. Using a mouse model, ciprofol treatment was shown to suppress macrophage polarization and decrease pro‐inflammatory cytokine levels, similar to the effects observed with the ...
Hanjian Chen +5 more
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A Retrospective study on Sedation and Anesthesia Practice in Ambulatory Surgery: Impact on Patient Comfort, Safety, and Recovery Time [PDF]
Objective: To evaluate the impact of sedation and anesthesia practices on patient comfort, intraoperative safety, and postoperative recovery time in ambulatory surgeries.
Khizra Tahreem +3 more
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