Results 21 to 30 of about 736 (146)

Comparison of Ciprofol-Based and Propofol-Based Total Intravenous Anesthesia on Microvascular Decompression of Facial Nerve with Neurophysiological Monitoring: A Randomized Non-Inferiority Trial [PDF]

Drug Design, Development and Therapy
Tao Zhu,1 Fang Kang,1 Ming-Ming Han,1 Fang He,2 Sen Jiang,2 Li-Na Hao,1 Xiang Huang,1 Juan Li1 1Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China ...
Zhu T, Kang F, Han MM, He F, Jiang S, Hao LN, Huang X, Li J   +7 more
doaj   +1 more source

Comparison of the efficacy and safety of ciprofol and propofol in sedating patients in the operating room and outside the operating room: a meta-analysis and systematic review

BMC Anesthesiology
Background As a new type of intravenous anesthetic, ciprofol has the advantages of fast onset of action, fast recovery and high clearance rate. This study aimed to investigate the effectiveness and safety of ciprofol versus traditional propofol for ...
Yanni Yang, Zekun Lang, Xiumei Wang, Peining Yang, Ning Meng, Yang Xing, Yatao Liu   +6 more
doaj   +2 more sources

Enhanced hemodynamic stability and patient satisfaction with ciprofol-remifentanil versus propofol-remifentanil for sedation in shorter-duration fiberoptic bronchoscopy: a prospective, randomized, double-blind study [PDF]

Frontiers in Medicine
ObjectiveThis study aimed to compare the efficacy and safety of ciprofol-remifentanil versus propofol-remifentanil in patients undergoing fiberoptic bronchoscopy (FOB).MethodsIn this prospective, randomized, double-blind, non-inferiority trial, 209 ...
Jia Nie, Yongguo Zhang, Yan Wang, Liang Fang, Huanhuan Ma, Yu Zhang, Hai-ying Wang   +6 more
doaj   +2 more sources

The effects of ciprofol on haemodynamics under general anaesthesia during thoracoscopic surgery: a randomised, double-blind, controlled trial

BMC Anesthesiology
Background Propofol, a widely administered sedative, is associated with potential hemodynamic instability during anaesthesia. Ciprofol introduces a cyclopropyl group to the chemical structure of propofol, forming an R-shaped hand structure and is ...
Lifang Lan, Jianping Liao, Liuying Qin, Xuemei Wang, Tan Qin, Yanhua Chen, Jingchen Liu   +6 more
doaj   +2 more sources

The Median Effective Dose of Ciprofol Combined with Sufentanil for Inhibiting Responses to Gastroscope Insertion in Obese Patients: A Prospective, Single-Center Study [PDF]

Drug Design, Development and Therapy
Zhouya Xue,1,2,* Xiang Liu,1,2,* Weisheng Qian,1 Nan Yang,1 Yongyi Pan,1 Yong Zhou,1 Wei Jiang,1 Feng Li,1 Bin Qian1 1Department of Anesthesiology, The First People’s Hospital of Yancheng, The Yancheng Clinical College of Xuzhou Medical ...
Xue Z, Liu X, Qian W, Yang N, Pan Y, Zhou Y, Jiang W, Li F, Qian B   +8 more
doaj   +1 more source

The 90% effective dose of ciprofol and propofol with S-ketamine for painless abortion: a randomized, double-blind, sequential dose-finding trial

Therapeutic Advances in Drug Safety
Background: Unlike the propofol–opioids combination, a single dose of S-ketamine with propofol achieves the same anesthetic effects while effectively minimizing adverse reactions in painless abortion.
Qiang Tao, Qiao Shi, Tao Xu, Shanshan Ye
doaj   +2 more sources

Safety and efficacy of ciprofol versus propofol for gastrointestinal endoscopy: a meta-analysis

BMC Gastroenterology
Background The role of ciprofol as a novel anesthetic in gastrointestinal endoscopic surgery is unclear. We conducted a systematic review and meta-analysis to evaluate the efficacy and safety of ciprofol for gastrointestinal endoscopy in patients aged ...
Xi Cheng, Pengyu Zhang, Dan Jiang, Baoxia Fang, Fuchao Chen   +4 more
doaj   +2 more sources

Ciprofol Ameliorates Myocardial Ischemia/Reperfusion Injury by Inhibiting Ferroptosis Through Upregulating HIF-1α [PDF]

Drug Design, Development and Therapy
Jun Ding,1– 3,* Bi-Ying Wang,1,2,* Yu-Fan Yang,1,2,* Ling-Yu Kuai,1,2 Jing-jie Wan,1,2 Mian Zhang,1,2 Hai-Yan Xia,3 Yao Wang,3 Zhong Zheng,3 Xiao-Wen Meng,1,2 Ke Peng,1,2 Fu-Hai Ji1,2 1Department of Anesthesiology, First Affiliated Hospital ...
Ding J, Wang BY, Yang YF, Kuai LY, Wan JJ, Zhang M, Xia HY, Wang Y, Zheng Z, Meng XW, Peng K, Ji FH   +11 more
doaj   +1 more source

Efficacy and safety of ciprofol for sedation/anesthesia in patients undergoing hysteroscopy: a prospective, randomized, non-inferiority trial

Annals of Medicine
Introduction Propofol is the preferred sedative for painless hysteroscopy and other procedures due to its fast onset and short duration. However, its limitations, including injection pain, respiratory depression, blood pressure decline, and bradycardia ...
Shi Cheng, Haixuan Wu, Zhongqi Liu, Dan Liu, Minghui Cao, Ganglan Fu   +5 more
doaj   +2 more sources

Intravenous Anesthesia with Ciprofol and Remimazolam Besylate for Painless Gastroscopy: A Prospective, Single-Center, Randomized Controlled Trial [PDF]

Drug Design, Development and Therapy
Lin Li,* Yusi Zhu,* Jie Zhu, Mingyue Zeng, Yu Duan, Pengfei Cheng, Xiang Zhou Department of Anesthesiology, General Hospital of Central Theater Command of PLA, Wuhan, People’s Republic of China*These authors contributed equally to
Li L, Zhu Y, Zhu J, Zeng M, Duan Y, Cheng P, Zhou X   +6 more
doaj   +1 more source