Comparative study of ciprofol vs. propofol in carotid endarterectomy: focusing on mean arterial pressure, vasoactive drug use, and postoperative complications [PDF]
Frontiers in MedicineAimThe aim of this study was to compare the effects of ciprofol and propofol on mean arterial pressure (MAP) management, vasoactive drug usage, and postoperative complications after carotid endarterectomy.MethodsA total of 103 patients were included in ...
Xinxin Zheng +4 more
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Enhanced hemodynamic stability and patient satisfaction with ciprofol-remifentanil versus propofol-remifentanil for sedation in shorter-duration fiberoptic bronchoscopy: a prospective, randomized, double-blind study [PDF]
Frontiers in MedicineObjectiveThis study aimed to compare the efficacy and safety of ciprofol-remifentanil versus propofol-remifentanil in patients undergoing fiberoptic bronchoscopy (FOB).MethodsIn this prospective, randomized, double-blind, non-inferiority trial, 209 ...
Jia Nie +6 more
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Ciprofol versus propofol and the risk of hemodynamic adverse events: a meta-analysis with trial sequential analysis of randomized controlled trials [PDF]
BMC AnesthesiologyIntroduction Intraoperative hypotension increases postoperative risks. Ciprofol, a novel anesthetic, has an onset and recovery profile comparable to propofol, but its potential superiority in mitigating intraoperative hypotension is unclear.
Minmin Zhu +3 more
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A Common Neuronal Ensemble in the Lateral Habenula Regulates Ciprofol Anesthesia in Mice
PharmaceuticalsGeneral anesthetics were first used over 170 years ago; however, the mechanisms of how general anesthetics induce loss of consciousness (LOC) remain unclear.
Kang Zhou +7 more
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Pharmacokinetics and pharmacodynamics of ciprofol after continuous infusion in elderly patients
BMC AnesthesiologyBackground Ciprofol, a novel intravenous anesthetic, which has primarily been used for the induction and maintenance of general anesthesia in adults, is characterized by rapid onset, short duration of action, and quick and smooth recovery.
Xiaowen Guo +6 more
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Effect of low-dose ciprofol on postoperative nausea and vomiting following gynecologic day surgery: a randomized controlled trial. [PDF]
Front Med (Lausanne)PurposeLow-dose propofol has a preventive effect on postoperative nausea and vomiting (PONV). Ciprofol is a new short-acting GABAA receptor agonist developed in China with a similar chemical structure to propofol, but its effect on PONV is unclear.
Shi X +10 more
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Comparison of Ciprofol-Based and Propofol-Based Total Intravenous Anesthesia on Microvascular Decompression of Facial Nerve with Neurophysiological Monitoring: A Randomized Non-Inferiority Trial [PDF]
Drug Design, Development and TherapyTao Zhu,1 Fang Kang,1 Ming-Ming Han,1 Fang He,2 Sen Jiang,2 Li-Na Hao,1 Xiang Huang,1 Juan Li1 1Department of Anesthesiology, the First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China ...
Zhu T +7 more
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Comparison of Ciprofol-Based and Propofol-Based Total Intravenous Anesthesia on Postoperative Recovery Quality in Patients Undergoing Hysteroscopic Surgery: A Randomized Non-Inferiority Trial [PDF]
Drug Design, Development and TherapyHuan Yang, Yan Yang, Yihao Huang, Tao Liu, Yiheng Wang Department of Anesthesiology, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang, Hunan, 421001, People’s Republic of ChinaCorrespondence: Yiheng Wang ...
Yang H, Yang Y, Huang Y, Liu T, Wang Y
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The Median Effective Dose of Ciprofol Combined with Sufentanil for Inhibiting Responses to Gastroscope Insertion in Obese Patients: A Prospective, Single-Center Study [PDF]
Drug Design, Development and TherapyZhouya Xue,1,2,* Xiang Liu,1,2,* Weisheng Qian,1 Nan Yang,1 Yongyi Pan,1 Yong Zhou,1 Wei Jiang,1 Feng Li,1 Bin Qian1 1Department of Anesthesiology, The First People’s Hospital of Yancheng, The Yancheng Clinical College of Xuzhou Medical ...
Xue Z +8 more
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Determination of the Median Effective Dose (ED50) of Ciprofol for Successful Sedation in Pediatric Patients During General Anesthesia Induction [PDF]
Drug Design, Development and TherapyPeihe Nie,1 Di Wu,2 Chengjun Du,1 Xiaoqian Wang,1 Huan Zhang,1 Hongyi Xiao1 1Department of Anesthesiology, Weifang People’s Hospital, Weifang, 261041, People’s Republic of China; 2Department of Outpatient, Weifang People’s Hospital, Weifang, 261041 ...
Nie P +5 more
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