Results 51 to 60 of about 670 (182)

Recovery Profiles and Well‐Being Outcomes in Patients Undergoing Various Anaesthesia Techniques: A Systematic Review

Health Science Reports, Volume 8, Issue 6, June 2025.
ABSTRACT Background and Aim An appropriate anaesthesia technique is considered for the patient's health status to ensure a painless recovery. This study explored the important role of anesthesia selection in improving recovery outcomes and patient well‐being across diverse surgical settings.
Abdullah K. Bubshait
wiley   +1 more source

Ciprofol suppresses glycolysis and EMT in colorectal cancer cells by activating APC to modulate the Wnt/β-catenin signaling pathway

Scientific Reports
Ciprofol, an innovative anesthetic derived from propofol, has not yet been studied in detail regarding its effects in colorectal cancer (CRC). This study mainly explored the effects of Ciprofol on the epithelial-mesenchymal transition (EMT) process ...
Han Wu, Jiening Gao, Yong Wang, Yao Zhang, Li Jia, Weijing Li   +5 more
doaj   +1 more source

Efficacy and safety comparison of esketamine-propofol with nalbuphine-propofol for upper gastrointestinal endoscopy in children: a multi-center randomized controlled trial [PDF]

, 2023
Background and AimsAnesthetics such as propofol, esketamine and nalbuphine are used during the upper gastrointestinal endoscopy to achieve and maintain the desired sedation level.
Jinjin Huang, Mazhong Zhang, Pan He, Sisi Wei, Xiaosu Zheng, Yang Shen, Yanting Wang, Ying Sun, Yingying Tao   +8 more
core   +1 more source

Pharmacokinetics and exposure–safety relationship of ciprofol for sedation in mechanically ventilated patients in the intensive care unit

CPT: Pharmacometrics &Systems Pharmacology, Volume 13, Issue 5, Page 823-836, May 2024.
Abstract Ciprofol (HSK3486) is a newly developed, highly selective γ‐aminobutyric acid‐A (GABAA) receptor potentiator that is recently approved for a new indication of sedation for patients in the intensive care unit (ICU) in China. This analysis aimed to characterize the population pharmacokinetics (PopPKs) of ciprofol and evaluate the relationship of
Lu Liu, Kun Wang, Zhongyi Sun, Pangke Yan, Mengyue Hu, Xiao Liu, Meixia Chen, Nan Wu, Xiaoqiang Xiang   +8 more
wiley   +1 more source

Effect of ciprofol on induction and maintenance of general anesthesia in patients undergoing kidney transplantation.

European review for medical and pharmacological sciences, 2022
This study aims at evaluating the effects of ciprofol on the induction and maintenance of general anesthesia in patients undergoing kidney transplantation.This prospective, randomized, single-blind study enrolled 120 patients aged 18-65 years who underwent general anesthesia for kidney transplantation. The patients were randomized into a ciprofol group
Qin, K., Qin, W.-Y., Ming, S.-P., Ma, X.-F., Du, X.-K.   +4 more
openaire   +2 more sources

Comparative analysis of the effect of electromyogram to bispectral index and 95% spectral edge frequency under remimazolam and propofol anesthesia: a prospective, randomized, controlled clinical trial [PDF]

, 2023
BackgroundBispectral index (BIS), an index used to monitor the depth of anesthesia, can be interfered with by the electromyogram (EMG) signal. The 95% spectral edge frequency (SEF95) also can reflect the sedation depth.
Aijun Xu, Cheng Liu, Li Ma, Miao Ma, Tianli Xie, Tiantian Chu, Yueyang Xin, Yuhui Liang   +7 more
core   +1 more source

Pharmacological Insights and Clinical Applications of Ciprofol: A Narrative Review

Cureus
Ciprofol (HSK3486) is a novel intravenous anaesthetic developed as an alternative to propofol, offering a safer and more effective option in anaesthesia. It works primarily by modulating the gamma-aminobutyric acid (GABA) receptors in the central nervous system, leading to sedation and hypnosis.
Petkar, Shubham, Bele, Amol, Priya, Vishnu, Bawiskar, Dushyant   +3 more
openaire   +2 more sources

ED50 of ciprofol combined with sufentanil for fiberoptic bronchoscopy of different patient populations with pulmonary tuberculosis

BMC Anesthesiology
Background Ciprofol is a promising sedative. This study aims to explore the median effective dose (ED50) of ciprofol in inhibiting responses to fiberoptic bronchoscopy in patients with pulmonary tuberculosis (PTB) of different genders and ages when ...
Min Pan, Weidong Liu, Zhixin Zhang, Tong Li, Weibin Xie   +4 more
doaj   +1 more source

The efficacy and safety of ciprofol use for the induction of general anesthesia in patients undergoing gynecological surgery: a prospective randomized controlled study

BMC Anesthesiology, 2022
Background Ciprofol is a recently developed, short-acting γ-aminobutyric acid receptor agonist sedative that is more potent than propofol, but there have been few clinical studies of this agent to date.
Ben-zhen Chen, Xin-yu Yin, Li-hua Jiang, Jin-hui Liu, Yan-yan Shi, Bi-ying Yuan   +5 more
doaj   +1 more source

Effect of ciprofol compared with propofol on hemodynamics in bronchoscope procedures during anesthetic induction: a randomized double-blind controlled study [PDF]

ObjectivePropofol poses hemodynamic challenges and injection pain during anesthesia. This study compared the effects of propofol and ciprofol, a novel propofol analog, on hemodynamics in painless bronchoscopy during induction of general anesthesia ...
Cheng Li, Fang Chen, Fang Xing, Jiayu Huang, Junwen Zhu, Ye Jiang   +5 more
core   +1 more source