Results 11 to 20 of about 96,820 (310)

m6A-modification regulated circ-CCT3 acts as the sponge of miR-378a-3p to promote hepatocellular carcinoma progression

open access: yesEpigenetics, 2023
Background: Circular RNA (circRNA) plays a critical role in tumour progression. Circ-CCT3, a particularly abundant circRNA, was proposed to be involved in tumorigenesis.
Hua Liu   +9 more
doaj   +2 more sources

CEAP-360VR: A Continuous Physiological and Behavioral Emotion Annotation Dataset for 360$^\circ$ VR Videos

open access: yesIEEE transactions on multimedia, 2023
Watching 360$^\circ$ videos using Virtual Reality (VR) head-mounted displays (HMDs) provides interactive and immersive experiences, where videos can evoke different emotions.
Tong Xue   +4 more
semanticscholar   +1 more source

Hypoxic ADSC-derived exosomes enhance wound healing in diabetic mice via delivery of circ-Snhg11 and induction of M2-like macrophage polarization.

open access: yesBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022
Diabetes mellitus is a major cause of blindness and chronic ulcers in the working age population worldwide. Former research have found that differentially expressed circular RNAs (circRNAs) are associated with hyperglycemia (HG)-induced endothelial cell ...
Rong-Feng Shi   +5 more
semanticscholar   +1 more source

circ-0000512 inhibits PD-L1 ubiquitination through sponging miR-622/CMTM6 axis to promote triple-negative breast cancer and immune escape

open access: yesJournal for ImmunoTherapy of Cancer, 2023
Background This study reported the function and mechanism of circ-0000512 in the progression of triple-negative breast cancer (TNBC). Methods circ-0000512 expression in TNBC tissues and paired adjacent normal tissues and cells was examined by qRT-PCR ...
Li-Feng Dong   +4 more
semanticscholar   +1 more source

Circ-EIF6 encodes EIF6-224aa to promote TNBC progression via stabilizing MYH9 and activating Wnt/beta-catenin pathway.

open access: yesMolecular Therapy, 2021
The protein-coding ability of circRNAs has recently been a hot topic, but the expression and roles of protein-coding circRNAs in triple-negative breast cancer (TNBC) remain uncertain. By intersecting circRNA sequencing data from clinical samples and cell
Yaming Li   +14 more
semanticscholar   +1 more source

Circ-ZEB1 promotes PIK3CA expression by silencing miR-199a-3p and affects the proliferation and apoptosis of hepatocellular carcinoma

open access: yesMolecular Cancer, 2022
Although the prognostic outcomes of liver cancer (LC) cases have improved with the advancement in diagnostic technology and treatment methods, the transferability and recurrence of HCC and the 5-year and 10-year survival rates of patients have remained ...
Weiwei Liu   +6 more
semanticscholar   +1 more source

Circular RNA circ‐TNPO3 inhibits clear cell renal cell carcinoma metastasis by binding to IGF2BP2 and destabilizing SERPINH1 mRNA

open access: yesClinical and Translational Medicine, 2022
Background Clear cell renal cell carcinoma (ccRCC) is a common malignant tumour of the urinary tract. The major causes of poor prognosis are the lack of early diagnosis and metastasis.
Xiaojuan Pan   +19 more
semanticscholar   +1 more source

Circular RNA circ-CPA4/ let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

open access: yesJournal of experimental & clinical cancer research : CR, 2020
Non-small cell lung cancer (NSCLC) cells derived intracellular and extracellular programmed cell death ligand 1 (PD-L1) promoted cancer progression and drug resistance, and facilitated tumor immune evasion.
Weijun Hong   +4 more
semanticscholar   +1 more source

Hypoxic pretreatment of adipose-derived stem cell exosomes improved cognition by delivery of circ-Epc1 and shifting microglial M1/M2 polarization in an Alzheimer’s disease mice model

open access: yesAging, 2022
Alzheimer’s disease (AD) is the most common dementia in the world. Increasing evidence has shown that exosomes from hypoxic pretreated adipose-derived stem cells (ADSCs) could be an effective cognitive function therapeutic in AD-associated ...
Haining Liu   +5 more
semanticscholar   +1 more source

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

open access: yesMolecules and Cells, 2017
Summary Circular RNAs (circRNAs) constitute a family of transcripts with unique structures and still largely unknown functions. Their biogenesis, which proceeds via a back-splicing reaction, is fairly well characterized, whereas their role in the ...
I. Legnini   +12 more
semanticscholar   +1 more source

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