Results 31 to 40 of about 96,820 (310)

The effectiveness of cooperative integrated reading and composition (CIRC) to improve writing in descriptive texts

ELT Forum: Journal of English Language Teaching, 2017
This paper is based on a study which investigated the eighth grade students’ achievement in writing descriptive text. The study aimed to find out the effectiveness of Cooperative Integrated Reading and Composition (CIRC) technique to teach writing of ...
Kamila Nurul Ibriza
doaj   +1 more source

circ-Pank1 promotes dopaminergic neuron neurodegeneration through modulating miR-7a-5p/α-syn pathway in Parkinson’s disease

Cell Death and Disease, 2022
Circular RNA (circRNA) is a type of non-coding RNA that is widely expressed in mammals. It is highly conserved and abundantly expressed in the brain. Here, we report the regulatory role of circRNA derived from the pantothenate kinase 1 (Pank1) gene (circ-
Qing Liu, Qiyao Li, Runjiao Zhang, Hongfang Wang, Yibo Li, Ziyu Liu, Wen Xie, Dandan Geng, Lei Wang   +8 more
semanticscholar   +1 more source

Circular RNA circ-TNPO3 suppresses metastasis of GC by acting as a protein decoy for IGF2BP3 to regulate the expression of MYC and SNAIL

Molecular Therapy: Nucleic Acids, 2021
Gastric cancer (GC) continues to be the most common gastrointestinal malignancy in China, and tumor metastases are a major reason for poor prognosis.
Ting Yu, Lingyu Ran, Hongwen Zhao, Pin Yin, Wei Li, Jie Lin, Hui Mao, Dongping Cai, Qiang Ma, Xia Pan, Xiaolin Wang, Jingjing Wu, H. Zeng, Wei-jun Zhang, D. Lu, P. Luo, Q. Zou, Bin Xiao   +17 more
semanticscholar   +1 more source

Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis

Arteriosclerosis, Thrombosis and Vascular Biology, 2021
Supplemental Digital Content is available in the text. Objective: Circular RNAs are emerging as important regulators of pulmonary hypertension where pyroptosis plays a critical role. However, whether and how the circular RNAs regulate pyroptosis remained
Yuan Jiang, Huiyu Liu, Hang Yu, Yang Zhou, Junting Zhang, W. Xin, Yiying Li, Siyu He, Cui Ma, Xiaodong Zheng, Lixin Zhang, Xijuan Zhao, Bingxiang Wu, Chun Jiang, Daling Zhu   +14 more
semanticscholar   +1 more source

The circular RNA circ-ERBIN promotes growth and metastasis of colorectal cancer by miR-125a-5p and miR-138-5p/4EBP-1 mediated cap-independent HIF-1α translation

Molecular Cancer, 2020
Background Circular RNA (circRNAs) and hypoxia have been found to play the key roles in the pathogenesis and progression of cancer including colorectal cancer (CRC).
Liang-Yan Chen, Lian Wang, Yue Ren, Zheng-Da Pang, Yao Liu, Xiao-Dong Sun, J. Tu, Zheng Zhi, Yan Qin, Lina Sun, Jianming Li   +10 more
semanticscholar   +1 more source

Circular RNA circ-ITCH inhibits bladder cancer progression by sponging miR-17/miR-224 and regulating p21, PTEN expression

Molecular Cancer, 2018
Circ-ITCH is a circRNA generated from several exons of itchy E3 ubiquitin protein ligase (ITCH) and tumor suppressor served as a sponge for certain miRNAs targeting their parental transcripts of ITCH. However, the role of circ-ITCH in bladder cancer (BCa)
Chengdi Yang, Wenbo Yuan, X. Yang, Peng Li, Jingzi Wang, Jie Han, J. Tao, Pengchao Li, Haiwei Yang, Q. Lv, Wei Zhang   +10 more
semanticscholar   +1 more source

Circ-TRIO promotes TNBC progression by regulating the miR-432-5p/CCDC58 axis

Cell Death and Disease, 2022
Numerous studies have shown that circRNAs are aberrantly expressed in various cancers and play a significant role in tumor progression. However, the molecular mechanisms of circRNAs in triple-negative breast cancer (TNBC) remain ambiguous.
Zekun Wang, Yaming Li, Jingwen Yang, Yiran Liang, Xiaolong Wang, Ning Zhang, Xiaoli Kong, Bing Chen, Lijuan Wang, Wenjing Zhao, Qifeng Yang   +10 more
semanticscholar   +1 more source

Circ‐CTNNB1 drives aerobic glycolysis and osteosarcoma progression via m6A modification through interacting with RBM15

Cell Proliferation, 2021
Circular RNAs (circRNAs) are a subclass of noncoding RNAs, playing essential roles in tumorigenesis and aggressiveness. Recent studies have revealed the pivotal functions of circ‐CTNNB1 (a circular RNA derived from CTNNB1) in cancer progression. However,
Feng Yang, Yangyang Liu, Jun Xiao, Bo Li, Yajun Chen, A. Hu, Jin Zeng, Zhili Liu, Hucheng Liu   +8 more
semanticscholar   +1 more source

Targeting circ-0034880-enriched tumor extracellular vesicles to impede SPP1highCD206+ pro-tumor macrophages mediated pre-metastatic niche formation in colorectal cancer liver metastasis

Molecular Cancer
Information transmission between primary tumor cells and immunocytes or stromal cells in distal organs is a critical factor in the formation of pre-metastatic niche (PMN).
Jing Zhou, Qing Song, Haoze Li, Yicun Han, Yunzhou Pu, Ling Li, Wenqing Rong, Xiaodie Liu, Ziyuan Wang, Jian-Yue Sun, Yuqing Song, Xueyan Hu, Guanghao Zhu, Huirong Zhu, Liu Yang, Guangbo Ge, Hongshan Li, Qing Ji   +17 more
semanticscholar   +1 more source

Circ-PKD2 promotes Atg13-mediated autophagy by inhibiting miR-646 to increase the sensitivity of cisplatin in oral squamous cell carcinomas

Cell Death and Disease, 2022
Autophagy is an evolutionally conserved catabolic process that degrades cells to maintain homeostasis. Cisplatin-activated autophagy promotes the expression of circ-PKD2, which plays a role as a tumor suppressor gene in the proliferation, migration, and ...
Ling Gao, Qian Zhang, Shaoming Li, Jingjing Zheng, W. Ren, K. Zhi   +5 more
semanticscholar   +1 more source