Results 151 to 160 of about 423,011 (334)

Hypnotic doses of fazamorexant induced less impairment on balance and cognition than zolpidem in healthy younger and elderly individualse

British Journal of Clinical Pharmacology, EarlyView.
Aims Fazamorexant is a dual orexin receptor antagonist being developed for the treatment of insomnia. This study aims to determine the dose‐exposure‐response relationship of single‐dose fazamorexant vs. zolpidem in young adult and elderly healthy Chinese volunteers. Methods This single‐centre, randomized, double‐blind, double‐dummy, placebo‐ and active‐
Chen Xia, Huang Xingxing, Jin Lu, Wang Ruwei   +3 more
wiley   +1 more source

The impact of urbanisation on social behaviour: a comprehensive review

Biological Reviews, EarlyView.
ABSTRACT Urbanisation is a key driver of global environmental change and presents animals with novel stressors and challenges. It can fundamentally influence social behaviour and has the potential to reshape within‐ and between‐species social interactions. Given the role of social behaviour in reproductive fitness and survival, understanding how social
Avery L. Maune, Barbara A. Caspers, Isabel Damas‐Moreira   +2 more
wiley   +1 more source

The possibility of circadian rhythm disruption in long COVID

Brain, Behavior, & Immunity - Health, 2022
Cathy A. Goldstein, David Kagan, Muneer Rizvydeen, Samuel Warshaw, Jonathan P. Troost, Helen J. Burgess   +5 more
doaj   +1 more source

Development of an electrocardiographic prediction model for outflow tract idiopathic premature ventricular contraction with decreased left ventricular ejection fraction

European Journal of Medical Research
Background The incidence of premature ventricular contraction (PVC) can be as high as 70% to 75% in general population. Even in the absence of any underlying heart disease, isolated ventricular premature contractions (IPVCs) can still lead to cardiac ...
Pinliang Liao, Xiaolian Cai, Wen Zhang, Min Ou, Heling Ren, Maoqin Shu   +5 more
doaj   +1 more source

Reading hominin life history in fossil bones and teeth: methods to test hypotheses regarding its evolution

Biological Reviews, EarlyView.
ABSTRACT Human life history is derived compared to that of our closest living relatives, the great apes. It has been suggested that these derived traits are causally related to aspects of our ecology, social behaviour and cognitive abilities. However, resolving this requires that we know the evolutionary trajectory of our distinctive pattern of growth,
Paola Cerrito, Judith M. Burkart, Carel van Schaik   +2 more
wiley   +1 more source

Modelling and Analysis of the Feeding Regimen Induced Entrainment of Hepatocyte Circadian Oscillators Using Petri Nets

, 2015
Samar Tareen, Jamil Ahmad
openalex   +2 more sources

The myth of the metabolic baseline: sleep–wake cycles undermine a foundational assumption in organismal biology

Biological Reviews, EarlyView.
ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman, Daphne Cortese, Amelia Munson, Jan Lindström, Shaun S. Killen   +4 more
wiley   +1 more source

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

Epilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud, Christophe Bernard, Birgit Frauscher, Philippa J. Karoly, Vikram R. Rao   +4 more
wiley   +1 more source

Dim light at night induces depression-like behaviors during the postpartum period through circadian rhythm related pathways in mice

Translational Psychiatry
Growing evidence suggests that dim light at night (dLAN) may disrupt circadian rhythms and provoke symptoms of anxiety and depression. Due to the inconvenience of pregnancy and caring for infants, there is a high prevalence of dLAN exposure among ...
Bingqin Lin, Nana Zheng, Biao Li, Wei Wang, Tong Luo, Yimei Fan, Ngan Yin Chan, Shitao Rao, Ying Yang, Hongliang Feng, Jihui Zhang   +10 more
doaj   +1 more source

Sleep and circadian rhythm characteristics in individuals from the general population during the French COVID‐19 full lockdown [PDF]

, 2021
L. Bertrand, Carmen Schröder, Patrice Bourgin, Julia Maruani, Yasmine Atoui, Marie‐Pia d’Ortho, Michel Lejoyeux, Pierre A. Geoffroy   +7 more
openalex   +1 more source