Two Decades of Optogenetic Tools: A Retrospective and a Look Ahead
Optogenetics provides up to millisecond scale, cell type‐specific control of biology using light‐sensitive proteins. This review chronicles two decades of tool development, from microbial rhodopsins and photoactivated enzymes to allosteric switches, surveys broad applications in neuroscience, molecular and cell biology, cardiology, immunology, and ...
Xiao Duan, Mo Zhu, Shiqiang Gao
wiley +1 more source
Circadian variation of serum glucose, C-peptide immunoreactivity and free insulin in normal and insulin-treated diabetic pregnant subjects [PDF]
Stephen B. Lewis+6 more
openalex +1 more source
Progress of non‐motor symptoms in early‐onset Parkinson's disease
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang+5 more
wiley +1 more source
Impact of Fish Oil and Flaxseed Oil on HIF-2α, COX-2 and IFN-γ Protein Expression: A Case Study in Rats With Kidney Damage Due to Circadian Rhythm Disorder. [PDF]
Erol Z+4 more
europepmc +1 more source
FIGO good practice recommendations on preconception care: A strategy to prevent preterm birth
Abstract Preterm birth (PTB) remains one of the leading causes of neonatal mortality and long‐term morbidity worldwide, with minimal progress being made in reducing its incidence, particularly in low‐resource settings. Preconception care is recognized as an effective strategy for PTB prevention; however, the fact that more than half of pregnancies ...
Leticia Irma Ojeda+21 more
wiley +1 more source
Effects of DNA methylation inhibitors on light-induced circadian clock plasticity. [PDF]
Kim S, McMahon DG.
europepmc +1 more source
Circadian Variation in Plasma 17-Hydroxyprogesterone in Patients with Congenital Adrenal Hyperplasia [PDF]
S. M. Atherden, N D Barnes, David Grant
openalex +1 more source
Microbiota humanization drives human‐like metabolic and immune transcriptomic shifts in pigs
This study successfully established gut microbiota‐humanized pigs, achieved human‐like remodeling of the serum metabolome, and uncovered transcriptional alterations in immune cell subsets. These findings advance our understanding of how human gastrointestinal microorganisms affect host metabolism and the immune function in a porcine model.
Zhaoqi Zhang+9 more
wiley +1 more source
Appropriate Lifelong Circadian Rhythms Are Established During Infancy: A Narrative Review. [PDF]
Miike T.
europepmc +1 more source
The Activity of Ribulose Diphosphate Carboxylase in Extracts of Gonyaulax polyedra in the Day and the Night Phases of the Circadian Rhythm of Photosynthesis [PDF]
Karen Bush, Beatrice M. Sweeney
openalex +1 more source