Light and circadian regulation of clock components aids flexible responses to environmental signals [PDF]
The circadian clock measures time across a 24h period, increasing fitness by phasing biological processes to the most appropriate time of day. The interlocking feedback loop mechanism of the clock is conserved across species; however, the number of loops
Akman, Ozgur E+5 more
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DNA damage and the circadian clock [PDF]
The role of the circadian clock has already been demonstrated for virtually all physiological processes, but it was only recently shown that cells were more sensitive to DNA damage at specific times of the day; that the peak of synthesis of mRNA and proteins of genes coding for products involved directly or indirectly in DNA repair was differentially ...
Chakarov,Stoyan+3 more
openaire +4 more sources
Epigenetic and posttranslational modifications in light signal transduction and the circadian clock in Neurospora crassa [PDF]
Blue light, a key abiotic signal, regulates a wide variety of physiological processes in many organisms. One of these phenomena is the circadian rhythm presents in organisms sensitive to the phase-setting effects of blue light and under control of the ...
Ballario, Paola+3 more
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Antagonistic Regulation of Circadian Output and Synaptic Development by JETLAG and the DYSCHRONIC-SLOWPOKE Complex [PDF]
Circadian output genes act downstream of the clock to promote rhythmic changes in behavior and physiology, yet their molecular and cellular functions are not well understood. Here we characterize an interaction between regulators of circadian entrainment,
Akpoghiran, Oghenerukevwe+3 more
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A Bioinformatics Approach [PDF]
By regulating the timing of cellular processes, the circadian clock provides a way to adapt physiology and behaviour to the geophysical time. In mammals, a light-entrainable master clock located in the suprachiasmatic nucleus (SCN) controls peripheral ...
Abreu, Monica+7 more
core +1 more source
Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for homeostasis because disruption or misalignment of the intrinsic rhythms is associated with the onset
Hyo Kyeong Cha+4 more
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Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal [PDF]
Every physiological function in the human body exhibits some form of circadian rhythmicity. Under pathological conditions, however, circadian rhythmicity may be dusrupted.
Ding, Jian M.+9 more
core +3 more sources
Rapid analysis of circadian phenotypes in Arabidopsis protoplasts transfected with a luminescent clock reporter [PDF]
The plant circadian clock allows the anticipation of daily changes to the environment. This anticipation aids the responses to temporally predictable biotic and abiotic stress.
Hansen, Louise L., Van Ooijen, Gerben
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Physcion Protects Against Ethanol-Induced Liver Injury by Reprogramming of Circadian Clock
The circadian clock plays a key role in our daily physiology and metabolism. Alcohol consumption disrupts the circadian rhythm of metabolic genes in the liver; however, the potential contribution of circadian clock modulation to alcoholic liver disease ...
Youli Yao+8 more
doaj +1 more source
Circadian Rhythm in Yeast [PDF]
Circadian rhythms are found in a variety of organisms and are involved in controlling activity of the organism. However, a circadian rhythm for yeast has not been discovered yet.
Borchert, Michael, Yablonowski, Jake
core +1 more source