Results 111 to 120 of about 301,259 (301)

The hormonal Zeitgeber melatonin: role as a circadian modulator in memory processing [PDF]

, 2012
The neuroendocrine substance melatonin is a hormone synthesized rhythmically by the pineal gland under the influence of the circadian system and alternating light/dark cycles. Melatonin has been shown to have broad applications, and consequently becoming
Rawashdeh, Oliver, Erik Maronde, Maronde, Erik, Oliver eRawashdeh, Erik eMaronde, Oliver Rawashdeh   +5 more
core   +1 more source

Blue Light Receptor PHR2‐Mediated Spectrum Antiviral Immunity

Advanced Science, EarlyView.
Blue light suppresses RBSDV through the blue‐light receptor ZmPHR2, which interacts with ZmISP in chloroplasts to trigger ROS burst and antiviral defense. The viral effector P6 enhances ZmPHR2–ZmISP interaction, alters their distribution, and suppresses ROS.
Runyi Chen, Yuxin Tai, Xinyu Wang, Chunhua Mu, Xia Liu, Gongjian Li, Jiayi Liu, Xin Lu, Duo Shi, Zhiqiang Zhou, Jienan Han, Zhuanfang Hao, Mingshun Li, Degui Zhang, Hongjun Yong, Zhennan Xu, Jianfeng Weng, Xinhai Li   +17 more
wiley   +1 more source

Quantitative analysis of regulatory flexibility under changing environmental conditions [PDF]

, 2010
The circadian clock controls 24-h rhythms in many biological processes, allowing appropriate timing of biological rhythms relative to dawn and dusk. Known clock circuits include multiple, interlocked feedback loops.
Andrew J Millar, Paul E Brown, David A Rand, Kirsten Knox, Knox, Kirsten, Thomson, Adrian W, Akman, Ozgur E, Lumsden, Peter J, Millar, A. J., Ozgur E Akman, Edwards, Kieron D, Brown, Paul E., Rand, D. A., Alexandra Pokhilko, Edwards, Kieron D., Thomson, Adrian W., Rand, David A, Lumsden, P. J., Nagy, Ferenc, Laszlo Kozma‐Bognar, Ra Pokhilko, Adrian W Thomson, Peter J Lumsden, Akman, Ozgur E., Kozma-Bognar, Laszlo, Kieron D Edwards, Ferenc Nagy, Pokhilko, Alexandra, Brown, Paul E, Millar, Andrew J; id_orcid, David A R, Laszlo Kozma-bognar   +31 more
core   +1 more source

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

Advanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong, Chen Lin, Wenjie Long, Ian Kim, Mengwen Xiong, Zuer Wu, Siyuan Rao, Qianbin Wang   +7 more
wiley   +1 more source

Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases

Frontiers in Molecular Neuroscience, 2019
Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for homeostasis because disruption or misalignment of the intrinsic rhythms is associated with the onset
Hyo Kyeong Cha, Sooyoung Chung, Hye Young Lim, Jong-Wha Jung, Gi Hoon Son   +4 more
doaj   +1 more source

Statistical inference of regulatory networks for circadian regulation [PDF]

, 2014
The work described in the present article is part of the TiMet project on linking the circadian clock to metabolism in plants. TiMet is a collaborative project (Grant Agreement 245143) funded by the European Commission FP7, in response to call FP7-KBBE ...
Aderhold, Andrej, Husmeier, Dirk, Grzegorczyk, Marco   +2 more
core   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source

Circadian coordination: understanding interplay between circadian clock and mitochondria

Animal Cells and Systems
Biological rhythms play a crucial role in temporally regulating behavioral, physiological, and cellular processes within our bodies. One prominent example is the circadian rhythm, which enables our bodies to anticipate external cues and regulate our ...
Jeongah Kim, Woong Sun
doaj   +1 more source

Circadian clock dysfunction and psychiatric disease: could fruit flies have a say?

Frontiers in Neurology, 2015
There is evidence of a link between the circadian system and psychiatric diseases. Studies in humans and mammals suggest that environmental and/or genetic disruption of the circadian system lead to an increased liability to psychiatric disease ...
Mauro Agostino Zordan, Mauro Agostino Zordan, Federica eSandrelli   +2 more
doaj   +1 more source

Diurnal rhythms in neurexins transcripts and inhibitory/excitatory synapse scaffold proteins in the biological clock [PDF]

, 2012
The neurexin genes (NRXN1/2/3) encode two families (α and β) of highly polymorphic presynaptic proteins that are involved in excitatory/inhibitory synaptic balance.
Hendricks, Michael, Shapiro-Reznik, Mika, Hadas Lerner, Anje Jilg, Jilg Anje, Earnest, David J., Earnest David J., Nava Zisapel, Zisapel, Nava, Lerner Hadas, Jilg, Anje, Mika Shapiro-Reznik, Zisapel Nava, Lerner, Hadas, David J Earnest, Shapiro-Reznik Mika   +15 more
core   +2 more sources