Results 91 to 100 of about 372,746 (304)

Photoperiodic plasticity in circadian clock neurons in insects

Frontiers in Physiology, 2013
Since Bünning’s observation of circadian rhythms and photoperiodism in the runner bean Phaseolus multiflorus in 1936, many studies have shown that photoperiodism is based on the circadian clock system.
Sakiko eShiga
doaj   +1 more source

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane, Valentina Giunchiglia, Michael C. B. David, Magdalena A. Kolanko, William R. Trender, Peter J. Hellyer, Harmeena Kaur, David J. Sharp, Christopher Carswell, Paresh A. Malhotra, Adam Hampshire   +10 more
wiley   +1 more source

Gut Microbiota-Derived Short Chain Fatty Acids Induce Circadian Clock Entrainment in Mouse Peripheral Tissue

Scientific Reports, 2018
Microbiota-derived short-chain fatty acids (SCFAs) and organic acids produced by the fermentation of non-digestible fibre can communicate from the microbiome to host tissues and modulate homeostasis in mammals.
Yu Tahara, M. Yamazaki, Haruna Sukigara, Hiroaki Motohashi, Hiroyuki Sasaki, Hiroki Miyakawa, Atsushi Haraguchi, Yuko Ikeda, S. Fukuda, S. Shibata   +9 more
semanticscholar   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

Arthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik, Abigail Bridgeman, Erik D. Herzog, Vy Pham, Bradley A. Evanoff, Farshid Guilak   +5 more
wiley   +1 more source

Effect of circadian clock disruption on type 2 diabetes

Frontiers in Physiology
IntroductionType 2 diabetes (T2D) is the predominant form of diabetes mellitus and is among the leading causes of death with an increasing prevalence worldwide. However, the pathological mechanism underlying T2D remains complex and unclear. An increasing
Hong Thuan Tran, Hong Thuan Tran, Takeru Kondo, Amal Ashry, Yunyu Fu, Hiroko Okawa, Chenphop Sawangmake, Chenphop Sawangmake, Chenphop Sawangmake, Hiroshi Egusa   +9 more
doaj   +1 more source

Emerging roles for microRNA in the regulation of Drosophila circadian clock

BMC Neuroscience, 2018
Background The circadian clock, which operates within an approximately 24-h period, is closely linked to the survival and fitness of almost all living organisms. The circadian clock is generated through a negative transcription-translation feedback loop.
Yongbo Xue, Yong Zhang
doaj   +1 more source

Stability of Medicinal Nanoemulsions to Spaceflight: Insights From the StarMed Experiment

Advanced Healthcare Materials, EarlyView.
Chitosan‐coated melatonin nanoemulsions (MN) recovered from a sounding rocket mission preserve droplet size and controlled‐release behavior, whereas uncoated nanoemulsions show ageing‐driven droplet growth and increased accessible drug fraction. Simple polymer coatings thus enhance the flight resilience of liquid space medicines under cumulative launch
Modupe Adebowale, Nguyen Van Duc Long, Philip M. Williams, Jens Hauslage, Volker Hessel   +4 more
wiley   +1 more source

Circadian synchronization between diet and gut microbiota in modulating host's health

Gut Microbes
Extensive research has established a complex relationship between the host, diet, and gut microbiota. Recent studies highlight the critical role of the host circadian clock in maintaining health.
Jianjun Ma, Yongkang Zhen, Yunan Weng, Jiaqi Lin, Chong Zhang, Yuhong Zhong, Jiaqi Zhou, Mengzhi Wang   +7 more
doaj   +1 more source

Evidence for widespread dysregulation of circadian clock progression in human cancer [PDF]

PeerJ, 2018
The ubiquitous daily rhythms in mammalian physiology are guided by progression of the circadian clock. In mice, systemic disruption of the clock can promote tumor growth. In vitro, multiple oncogenes can disrupt the clock.
Jarrod Shilts, Guanhua Chen, Jacob J. Hughey   +2 more
doaj   +2 more sources

Role of Sleep Restriction in Daily Rhythms of Expression of Hypothalamic Core Clock Genes in Mice

Current Issues in Molecular Biology, 2022
Lack of sleep time is a menace to modern people, and it leads to chronic diseases and mental illnesses. Circadian processes control sleep, but little is known about how sleep affects the circadian system.
Weitian Li, Zixu Wang, Jing Cao, Yulan Dong, Yaoxing Chen   +4 more
doaj   +1 more source