Results 131 to 140 of about 347,727 (386)

DNA damage and the circadian clock [PDF]

open access: yesBioDiscovery, 2014
The role of the circadian clock has already been demonstrated for virtually all physiological processes, but it was only recently shown that cells were more sensitive to DNA damage at specific times of the day; that the peak of synthesis of mRNA and proteins of genes coding for products involved directly or indirectly in DNA repair was differentially ...
Chakarov,Stoyan   +3 more
openaire   +4 more sources

Amino Acid‐Sensing Neurons in the Anterior Piriform Cortex Control Brown Adipose Tissue Thermogenesis

open access: yesAdvanced Science, EarlyView.
This study identifies a class of amino acid‐sensing neurons, APCCRH neurons, which regulate BAT thermogenesis. Leucine deficiency alters intrinsic excitability through GCN2 signaling pathway, activating APCCRH neurons, which in turn regulate BAT thermogenesis via projections to the lateral hypothalamus.
Peixiang Luo   +15 more
wiley   +1 more source

Barley Hv CIRCADIAN CLOCK ASSOCIATED 1 and Hv PHOTOPERIOD H1 Are Circadian Regulators That Can Affect Circadian Rhythms in Arabidopsis. [PDF]

open access: yesPLoS ONE, 2015
Circadian clocks regulate many aspects of plant physiology and development that contribute to essential agronomic traits. Circadian clocks contain transcriptional feedback loops that are thought to generate circadian timing.
Jelena Kusakina   +7 more
doaj   +1 more source

Influence of photic perturbations on circadian rhythms [PDF]

open access: yesarXiv, 2019
The circadian clock is the molecular mechanism responsible for the adaptation to daily rhythms in living organisms. Oscillations and fluctuations in environmental conditions regulate the circadian clock through signaling pathways. We study the response to continuous photic perturbations in a minimal molecular network model of the circadian clock ...
arxiv  

Circadian Clock Control of Liver Metabolic Functions.

open access: yesGastroenterology, 2016
The circadian clock is an endogenous biological timekeeping system that synchronizes physiology and behavior to day/night cycles. A wide variety of processes throughout the entire gastrointestinal tract and notably the liver appear to be under circadian ...
H. Reinke, Gad Asher
semanticscholar   +1 more source

Overcoming Extreme Ammonia Inhibition on Methanogenesis by Artificially Constructing a Synergistically Community with Acidogenic Bacteria and Hydrogenotrophic Archaea

open access: yesAdvanced Science, EarlyView.
This study proposes a two‐step biological strategy to synergistically enhance the three stages of anaerobic digestion, ultimately eliminating the extreme ammonia inhibition and breaking through the inefficiency bottleneck of conventional biotechnology.
Heng Wu   +6 more
wiley   +1 more source

Small Molecule Modulators of the Circadian Molecular Clock With Implications for Neuropsychiatric Diseases

open access: yesFrontiers in Molecular Neuroscience, 2019
Circadian rhythms regulate many biological processes and play fundamental roles in behavior, physiology, and metabolism. Such periodicity is critical for homeostasis because disruption or misalignment of the intrinsic rhythms is associated with the onset
Hyo Kyeong Cha   +4 more
doaj   +1 more source

Advanced Microfluidic‐Based Wearable Electrochemical Sensors for Continuous Biochemical Monitoring

open access: yesAdvanced Electronic Materials, EarlyView.
Microfluidic‐based wearable electrochemical sensors are transforming non‐invasive health monitoring through real‐time biochemical analysis of sweat, saliva, and interstitial fluid. This review explores advances in microfluidic design, fabrication, and sensor integration while addressing biofluid variability, material compatibility, and scalability.
Sehyun Park   +5 more
wiley   +1 more source

The accuracy of telling time via oscillatory signals [PDF]

open access: yes, 2016
Circadian clocks are the central timekeepers of life, allowing cells to anticipate changes between day and night. Experiments in recent years have revealed that circadian clocks can be highly stable, raising the question how reliably they can be read out.
arxiv   +1 more source

A Case of Prader‐Willi Syndrome With a Deletion Including MAGEL2, NDN, and MKRN3, but Excluding SNRPN and SNORD116

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Prader‐Willi syndrome (PWS) is a neurodevelopmental disorder typically caused by large deletions or imprinting defects on chromosome 15q11.2, encompassing multiple genes. While the contribution of individual genes to the PWS phenotype remains unclear, previous studies suggested that isolated deletions of MAGEL2, NDN, and MKRN3, excluding the ...
Jannis Buecking   +6 more
wiley   +1 more source

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