Results 131 to 140 of about 120,096 (334)

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

The emergence of circadian timekeeping in the intestine

Nature Communications
The circadian clock is a molecular timekeeper, present from cyanobacteria to mammals, that coordinates internal physiology with the external environment.
Kathyani Parasram, Amy Zuccato, Minjeong Shin, Reegan Willms, Brian DeVeale, Edan Foley, Phillip Karpowicz   +6 more
doaj   +1 more source

Ontogeny of the circadian clock in Sarcophaga crassipalpis [PDF]

, 2016
The timing of circadian rhythms is controlled by the rhythmic expression of clock genes in pacemaker neurons within the brain. Circadian gene expression and behavior can entrain to thermoperiod and photoperiod.
Short, Clancy
core  

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

Advanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu, Yuqi He, Wenfeng Weng, Zebin Liu, Yuanfen Gao, Yaliang Shi, Wei Li, Dili Lai, Mengyu Zhao, Rintu Jha, Hui Zhao, Guangsheng Li, Chaonan Guan, Shuai Shao, Jingjun Ruan, Sun Hee Woo, Yinan Ouyang, Muriel Quinet, Milen I. Georgiev, Alisdair R. Fernie, Congcong Hou, Kaixuan Zhang, Xu Liu, Meiliang Zhou   +23 more
wiley   +1 more source

Quantification of circadian rhythms in mammalian lung tissue snapshot data

Scientific Reports
Healthy mammalian cells have a circadian clock, a gene regulatory network that allows them to schedule their physiological processes to optimal times of the day.
Saskia Grabe, Bharath Ananthasubramaniam, Hanspeter Herzel   +2 more
doaj   +1 more source

CREB Influences Timing and Entrainment of the SCN Circadian Clock [PDF]

, 2010
Boyoung Lee, Aiqing Li, Katelin F. Hansen, Ruifeng Cao, Jae Hwa Yoon, Karl Obrietan   +5 more
openalex   +1 more source

Plant Robotics for Sustainable and Environmentally Friendly Robots: Insights from Actuation Characteristics

Advanced Science, EarlyView.
Plants are promising materials for building sustainable and eco‐friendly robots due to their inherent multifunctionality, with actuation playing a crucial role. This article focuses on the physical movements of plants and, from the perspective of actuation characteristics, explores representative plant species and their behaviors, the current state of ...
Kazuya Murakami, Misao Sato, Yu Ikeda, Tatsuhiro Horii, Yukari Nagatoshi, Miki Fujita, Toshinori Fujie, Yasunari Fujita, Jun Shintake   +8 more
wiley   +1 more source

Affinity‐Based Protein Profiling Revealed that HIGD1A is a Direct Target Protein of Aristolochic Acids

Advanced Science, EarlyView.
Using an affinity‐based probe, this study reveals that aristolochic acid directly binds to HIGD1A with high affinity in the kidney. This binding disrupts the HIGD1A‐TFAM interaction, which in turn triggers TFAM degradation, cytosolic mitochondrial DNA release, and the activation of inflammatory pathways. Abstract Exposure to aristolochic acids (AA) via
Yin Gong, Shanshan Zhang, Anying Wei, Xiang Ji, Xiaodan Chong, Jinfeng Cen, Xuan Zhao, Zimeng Luo, Zhipeng Pei, Guanchao Mao, Xinkang Zhang, Mingxue Sun, Zhiguo Sun, Zifei Yin, Zhengrong Zou, Wen‐Qi Meng   +15 more
wiley   +1 more source

Circadian light-input pathways in Drosophila

Communicative & Integrative Biology, 2016
Light is the most important environmental cue to entrain the circadian clock in most animals. In the fruit fly Drosophila melanogaster, the light entrainment mechanisms of the clock have been well-studied.
Taishi Yoshii, Christiane Hermann-Luibl, Charlotte Helfrich-Förster   +2 more
doaj   +1 more source

Ionic–Bionic Interfaces: Advancing Iontronic Strategies for Bioelectronic Sensing and Therapy

Advanced Science, EarlyView.
Ionic–bionic interfaces for bioelectronics leverage ions as multifunctional mediators that combine mechanical compliance, ionic and electronic functionalities, and therapeutic effects. These systems offer real‐time biosignal transduction, effective wound dressing, responsive drug delivery, and seamless interaction between soft tissues and electronic ...
Yun Goo Ro, Yoojin Chang, Jeeyoon Kim, Seungjae Lee, Sangyun Na, Cheolhong Park, Hyunhyub Ko   +6 more
wiley   +1 more source