Results 141 to 150 of about 114,755 (253)

Circadian rhythmic kinase CK2α phosphorylates BMAL1 to regulate the mammalian clock [PDF]

open access: yes, 2008
Clock proteins govern circadian physiology and their function is regulated by a variety of signaling pathways. Here, we show that p45^PFK^, a previously reported circadian rhythmic kinase, corresponds to CK2[alpha].
Jun Hirayama   +6 more
core  

SnapShot: Circadian Clock Proteins

open access: yesCell, 2008
The earth’s rotation about its axis generates predictable changes in light and temperature, which define the 24 hr day-night cycle. Organisms from bacteria to humans have evolved an internal timekeeper to anticipate these environmental changes. This timekeeper—the circadian clock—allows organisms to parse biological processes to the appropriate time of
Steve A. Kay, Elizabeth E. Hamilton
openaire   +2 more sources

The emergence of circadian timekeeping in the intestine

open access: yesNature Communications
The circadian clock is a molecular timekeeper, present from cyanobacteria to mammals, that coordinates internal physiology with the external environment.
Kathyani Parasram   +6 more
doaj   +1 more source

Quantification of circadian rhythms in mammalian lung tissue snapshot data

open access: yesScientific Reports
Healthy mammalian cells have a circadian clock, a gene regulatory network that allows them to schedule their physiological processes to optimal times of the day.
Saskia Grabe   +2 more
doaj   +1 more source

Hepatic gene therapy rescues high-fat diet responses in circadian Clock mutant mice

open access: yesMolecular Metabolism, 2017
Objective: Circadian Clock gene mutant mice show dampened 24-h feeding rhythms and an increased sensitivity to high-fat diet (HFD) feeding. Restricting HFD access to the dark phase counteracts its obesogenic effect in wild-type mice.
Judit Meyer-Kovac   +9 more
doaj   +1 more source

EVOLUTION OF THE CIRCADIAN CLOCK IN EXTREME ENVIRONMENT: LESSONS FROM CAVEFISH. [PDF]

open access: yes, 2010
Evolution has been strongly influenced by the daily cycles of temperature and light imposed by the rotation of the Earth. Fascinating demonstrations of this are seen in extreme environments such as caves where some animals have remained completely ...
Cavallari, Nicola
core  

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