Results 161 to 170 of about 301,259 (301)

Peripheral inflammatory markers and metabolic profiles in temporal lobe epilepsy and functional dissociative seizures

open access: yesEpileptic Disorders, EarlyView.
Abstract Background Temporal lobe epilepsy (TLE) and functional dissociative seizures (FDS) are distinct conditions that share overlapping clinical, neuropsychiatric, and biological features, including depressive symptoms, obesity‐related metabolic dysregulation, and alterations in systemic inflammatory markers.
Betül Merd   +6 more
wiley   +1 more source

Artificial intelligence for adaptive neuromodulation in drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects nearly one third of people with epilepsy and is associated with substantial cognitive, psychiatric, and mortality burdens. For patients who are not candidates for resection or laser interstitial thermal therapy, neuromodulation therapies such as vagus nerve stimulation, deep brain stimulation, and ...
Amir Hossein Daraie   +10 more
wiley   +1 more source

Seizure forecasting: The long and winding road to clinical translation

open access: yesEpilepsia, EarlyView.
Abstract Seizure forecasting has progressed from theoretical aspiration to a rapidly advancing research domain, yet clinical translation remains limited. Over the past decades, advances in algorithm development, chronic electroencephalography (EEG), wearable sensors, and the characterization of seizure cycles have demonstrated that seizure risk is not ...
Philippa J. Karoly   +7 more
wiley   +1 more source

Monthly or menstrual? A scoping review of catamenial epilepsy and non‐menstrual seizure rhythms

open access: yesEpilepsia, EarlyView.
Abstract Objective Despite the reported high prevalence of catamenial epilepsy (CE), the condition remains poorly defined, with lack of consensus on what entails a menstrual‐related seizure exacerbation. Emerging evidence of multiday cycles of seizure activity, including about‐monthly cycles, present in both men and women, further confound the ...
Victoria Wong   +4 more
wiley   +1 more source

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia   +19 more
wiley   +1 more source

Repetitive clustered low‐voltage fast activity on intracranial electroencephalogram in mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy: A candidate electroencephalographic biomarker study

open access: yesEpilepsia, EarlyView.
Abstract Objective Mild malformation of cortical development with oligodendroglial hyperplasia and epilepsy (MOGHE) is a recently recognized cause of drug‐resistant focal epilepsy. It is often magnetic resonance imaging‐negative or radiologically resembles focal cortical dysplasias, which makes recognition difficult and limits presurgical counseling ...
Vadym Gnatkovsky   +25 more
wiley   +1 more source

Chemogenetic activation of parvalbumin interneurons in the piriform cortex alleviates hippocampal focal seizures

open access: yesEpilepsia, EarlyView.
Abstract Objective The anterior piriform cortex (APC) is a limbic area closely associated with temporal lobe epilepsy (TLE) but is understudied. Our previous study demonstrated that in the APC, parvalbumin‐expressing (PV+) interneurons provide strong inhibition and help maintain excitation–inhibition balance.
Huiqi Zhang   +3 more
wiley   +1 more source

Implications of Intermittent Fasting on Placental Function [PDF]

open access: yes
Introduction: Women who partake in Ramadan during pregnancy have lower placental weights. Intermittent fasting (IF) impacts upon asynchronous dietary cues and the entrained sleep cycle.
Sansby, Luke
core   +1 more source

Seizure quantification using wearable devices

open access: yesEpilepsia, EarlyView.
Abstract Accurate assessment of seizure occurrence is central to treatment optimization, risk stratification, and management of epilepsy, yet remains largely dependent on patient‐reported seizure diaries, which are frequently incomplete and unreliable.
Jesper Jeppesen   +4 more
wiley   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus   +7 more
wiley   +1 more source

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