Results 171 to 180 of about 48,399 (260)

Perturbation of the circadian clock in chronic diseases involving organ fibrosis. [PDF]

J Clin Invest
Mukherji A, Tharaux PL, Ray DW, Baumert TF.   +3 more
europepmc   +1 more source

Effects of timed LED regimes on tomato plant traits, performance of two‐spotted spider mites, and predatory mites (Phytoseiulus persimilis)

Pest Management Science, Volume 81, Issue 4, Page 2300-2311, April 2025.
Light‐emitting diode (LED)‐based treatments for enhancing crop production and pest management have primarily focused on continuous treatments. This study, using Tetranychus urticae and Phytoseiulus persimilis, demonstrates that the timing of LED supplementation is crucial for designing integrated pest management strategies that improve both plant ...
Patrice Savi, Samantha Hall, Maria Hernandez, Anil Mantri, Daniel Kliebenstein, Christian Nansen   +5 more
wiley   +1 more source

Paf1C regulates the Neurospora circadian clock by promoting the transcription elongation of frequency. [PDF]

PLoS Genet
Zhou M, Zhao Y, He Y, Duan Z, Liu X, He Q.   +5 more
europepmc   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen, Chaozhuang Shen, Yuchen Tian, Yuhe Peng, Jing Hu, Haitang Xie, Ping Yin   +6 more
wiley   +1 more source

Construction of circadian clock signature for tumor microenvironment in predicting survival of esophageal squamous cell carcinoma. [PDF]

Front Immunol
Xiang Y, Cui X, Cui Z.
europepmc   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Steroid hormone receptors through Cry2 are key players in the circadian clock response to serum. [PDF]

Nat Commun
Manella G, Ezagouri S, Bolshette N, Kramer A, Golik M, Adamovich Y, Asher G.   +6 more
europepmc   +1 more source

Exploring Linalool‐Based Phytotherapy for Excitatory/Inhibitory Imbalance in Alzheimer's Disease: A Review of Lavender and Cannabis Therapeutic Effects on Sleep, Seizures, and Cognition

Phytotherapy Research, EarlyView.
Schematic overview of the proposed neuromodulatory actions of linalool in Alzheimer's disease. Through multi‐target effects on oxidative stress, amyloid aggregation, GABAergic and glutamatergic signaling, linalool may restore excitatory/inhibitory balance.
Ilaria Piccialli, Giovanni Roviello, Giorgia Magliocca, Emilia Esposito, Anna Pannaccione   +4 more
wiley   +1 more source

Circadian clock genes: Their influence on liver metabolism, disease development and treatment (Review). [PDF]

Mol Med Rep
Wang J, Cao M, Li S, Pei W, Li J, Wang Z.   +5 more
europepmc   +1 more source

Cameras do not always take a full picture: wolf activity patterns revealed by accelerometers versus road‐positioned camera traps

Remote Sensing in Ecology and Conservation, EarlyView.
Camera traps have become an increasingly popular non‐invasive alternative to animal‐attached devices for studying wildlife behaviour. This study compared wolf (Canis lupus) activity patterns derived from collar accelerometers and road‐positioned camera traps and revealed strong overall agreement but also important seasonal and diel mismatches between ...
Katarzyna Bojarska, Michał Żmihorski, Morteza Naderi, J. David Blount, Mark Chynoweth, Emrah Coban, Çağan H. Şekercioğlu, Josip Kusak   +7 more
wiley   +1 more source