Results 161 to 170 of about 402,265 (407)

Fresh insights into the light‐induced pineal gland circadian rhythm transmission mechanism derived from mRNA and miRNA profiling

Animal Research and One Health, EarlyView.
Mechanisms of light in regulating the chick pineal clock. Abstract The circadian clock significantly impacts animal health and productivity, with light playing a crucial role in regulating circadian rhythms. However, the mechanisms behind light‐induced circadian transmission remain unclear, particularly in light‐sensitive avian species.
Yunlei Li, Yanyan Sun, Jingwei Yuan, Xiangchen Li, Lei Shi, Adamu Mani Isa, Yuanmei Wang, Pingzhuang Ge, Yunhe Zong, Panlin Wang, Jilan Chen   +10 more
wiley   +1 more source

Genetic insights on sleep schedules: this time, it's PERsonal. [PDF]

, 2012
The study of circadian rhythms is emerging as a fruitful opportunity for understanding cellular mechanisms that govern human physiology and behavior, fueled by evidence directly linking sleep disorders to genetic mutations affecting circadian molecular ...
Chong, SY Christin, Fu, Ying-Hui, Ptáček, Louis J   +2 more
core   +1 more source

Cellular mechano-environment regulates the mammary circadian clock

Nature Communications, 2017
Circadian clocks drive ∼24 h rhythms in tissue physiology. They rely on transcriptional/translational feedback loops driven by interacting networks of clock complexes.
N. Yang, Jack L. Williams, Vanja Pekovic-Vaughan, Pengbo Wang, S. Olabi, J. McConnell, N. Gossan, A. Hughes, J. Cheung, C. Streuli, Q. Meng   +10 more
semanticscholar   +1 more source

Entrainment of the Arabidopsis Circadian Clock [PDF]

Journal of Plant Biology, 2009
The rising and setting of the sun marks a transition between starkly contrasting environmental conditions for vegetative life. Given these differing diurnal and nocturnal environmental factors and the inherent regularity of the transition between the two, it is perhaps unsurprising that plants have developed an internal timing mechanism (known as a ...
openaire   +5 more sources

Medications, epilepsy and climate change: Added layers of complexity

British Journal of Clinical Pharmacology, EarlyView.
Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi, Seyhmus Gavas, Sanjay M. Sisodiya   +2 more
wiley   +1 more source

The emergence of circadian timekeeping in the intestine

Nature Communications
The circadian clock is a molecular timekeeper, present from cyanobacteria to mammals, that coordinates internal physiology with the external environment.
Kathyani Parasram, Amy Zuccato, Minjeong Shin, Reegan Willms, Brian DeVeale, Edan Foley, Phillip Karpowicz   +6 more
doaj   +1 more source

A conserved circadian function for the Neurofibromatosis 1 gene [PDF]

, 2018
Summary: Loss of the Neurofibromatosis 1 (Nf1) protein, neurofibromin, in Drosophila disrupts circadian rhythms of locomotor activity without impairing central clock function, suggesting effects downstream of the clock.
Bai, Lei, Cavanaugh, Daniel, Gutmann, David H, Haynes, Paula, Hsu, Cynthia T, Lee, Yool, Sehgal, Amita, Stein, Carly, Wang, Han, Williams, Julie A, Zheng, Xiangzhong   +10 more
core   +3 more sources

ISOLATION OF CIRCADIAN CLOCK MUTANTS OF NEUROSPORA CRASSA [PDF]

, 1973
Jerry F. Feldman, Marian Hoyle
openalex   +1 more source

Dynamic Compression Improves Chondrogenesis in the Tissue Engineered Model of Cartilage

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hyaline cartilage is a dense avascular tissue with low regenerative potential, present at the ends of the diarthrodial joints and in the cartilage growth plate. Skeletal diseases often result from extracellular changes in this tissue; however, studies of these are hindered by the tissue complexity, the difficulty in obtaining human material ...
Marc V. Farcasanu, Thais de las Heras Ruiz, Francesca M. Johnson de Sousa Brito, Jamie Soul, Jonathan Coxhead, Matthew J. German, David A. Young, Ana M. Ferreira‐Duarte, Katarzyna A. Piróg   +8 more
wiley   +1 more source

The Circadian Clock Mutation Promotes Intestinal Dysbiosis.

Alcoholism: Clinical and Experimental Research, 2016
BACKGROUND Circadian rhythm disruption is a prevalent feature of modern day society that is associated with an increase in pro-inflammatory diseases, and there is a clear need for a better understanding of the mechanism(s) underlying this phenomenon.
R. Voigt, Keith C. Summa, C. Forsyth, S. Green, P. Engen, A. Naqib, M. Vitaterna, F. Turek, A. Keshavarzian   +8 more
semanticscholar   +1 more source