Results 161 to 170 of about 109,508 (306)

Circadian Clocks [PDF]

Cell, 2001
Merrow, Martha, Roenneberg, Till
openaire   +1 more source

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

Epilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud, Christophe Bernard, Birgit Frauscher, Philippa J. Karoly, Vikram R. Rao   +4 more
wiley   +1 more source

Spectral entropy variability of intraoperative electrocorticography predicts outcome after epilepsy surgery in people with focal cortical dysplasia

Epilepsia, EarlyView.
Abstract Objective Epilepsy surgery in people with focal cortical dysplasia (FCD) requires accurate removal of all epileptogenic tissue, and outcome is difficult to predict. We explored whether spectral entropy, a fast computable electroencephalographic (EEG) feature, could estimate epileptic activity in intraoperative electrocorticography (ioECoG) and
Eline V. Schaft, Sem Hoogteijling, Dongqing Sun, Cyrille H. Ferrier, Pieter van Eijsden, Wim M. Otte, Galia Anguelova, Nick F. Ramsey, Maryse A. van't Klooster, Maeike Zijlmans, on behalf of the RESPect database study group, Charlotte van Asch, Lydia van de Berg, Dorien van Blooijs, Kim Boshuisen, Mireille Bourez, Kees Braun, Jan Willem Dankbaar, Matteo Demuru, Pieter van Eijsden, Cyrille Ferrier, Tineke Gebbink, Fernando Gomez‐Acebo Ruiz, Peter Gosselaar, Kimberley Grasmeijer, Renate van Griethuysen, Jiaojiao Guo, Irene Heijink, Monique Hobbelink, Friso Hoefnagels, Sem Hoogteijling, Geertjan Huiskamp, Sarah Jacobs, Floor Jansen, Susanne Jelsma, Nicole van Klink, Merel Koopmans, Frans Leijten, Wouter Maathuis, Mariska Mantione, Angelika Muhlebner, Brechje Olgers, Janine van Ophorst, Miranda Postma, Sandra van der Salm, Eline Schaft, Anniek van Schaik, Monique van Schooneveld, Dongqing Sun, Ziyi Wang, Martine van Zandvoort, Eva Zuidhoek, Willemiek Zweiphenning, Jack Zwemmer   +53 more
wiley   +1 more source

Seizure forecasting with epilepsy cycles: On the causality of forecasting pipelines

Epilepsia, EarlyView.
Abstract Objective Seizure risk is modulated by multiscale brain rhythms. Previous studies using cycles in electroencephalography, heart rate, and wearable data suggest the possibility of forecasting seizures days in advance. However, they commonly rely on methods requiring (days of) information from time points beyond the moment of forecast (noncausal
Hongliu Yang, Jens Müller, Sotirios Kalousios, Georg Leonhardt, Matthias Dümpelmann, Andreas Schulze‐Bonhage, Ronald Tetzlaff   +6 more
wiley   +1 more source

Rhythms in longitudinal thalamic recordings are linked to seizure risk

Epilepsia, EarlyView.
Abstract Objective Seizure unpredictability remains a major clinical challenge for people with epilepsy. Previous works have shown that seizure risk is associated with circadian and multi‐day cycles in both brain and physiological signals. However, it remains unclear whether neural activity from deep brain structures such as the anterior nucleus of the
Xinbing Zhang, Zachary T. Sanger, Thomas Lisko, Steffen Ventz, Robert A. McGovern, Theoden I. Netoff   +5 more
wiley   +1 more source

Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges

Epilepsia Open, EarlyView.
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus, Cesar Santana‐Gomez, Ruby G. Escalante, Dominique Duncan, Pedro F. Viana, Giulia Sofia Cereda, Naoto Kuroda, Aristea S. Galanopoulou   +7 more
wiley   +1 more source

Prenatal betamethasone–postnatal N‐methyl‐D‐aspartic acid model of spasms: Update on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Infantile epilepsy spasms syndrome (IESS), formerly known as infantile spasms or West Syndrome, is a severe epilepsy syndrome affecting about 3 in 10,000 newborns in the United States. Characterized by clusters of epileptic spasms, interictal hypsarrhythmia, and developmental delays, IESS has diverse causes, including structural‐metabolic ...
Kayla Vieira, Antonia Schonwald, Chian‐Ru Chern, Kamya Shah, Jana Velíšková, Libor Velíšek   +5 more
wiley   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Fast ripple‐delta coupling as an early biomarker for post‐traumatic epileptogenesis in repetitive brain injury

Epilepsia Open, EarlyView.
Abstract Objective Traumatic brain injury (TBI) can induce posttraumatic epilepsy (PTE), but early biomarkers for epileptogenesis are lacking. We aimed to investigate electrographic biomarkers before and during posttraumatic seizure development. Methods We used a repetitive diffuse TBI model in mice with continuous video‐EEG monitoring up to 4½ months ...
Oleksii Shandra, Dzenis Mahmutovic, Biswajit Maharathi, Md Adil Arman, Michael J. Benko, Owen Leitzel, Pritom Kumar Saha, Stefanie Robel   +7 more
wiley   +1 more source

Faecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen, Nele M. Korten, Larissa Blischke, Clara Voelz, Cordian Beyer, Jochen Seitz, Stefanie Trinh   +6 more
wiley   +1 more source