Results 191 to 200 of about 113,418 (363)

STIP1 drives Metabolic Reprogramming in Esophageal Squamous Cell Carcinoma via AHCY‐LDHA Axis

Exploration, EarlyView.
A schematic model illustrating that LCA can inhibit ESCC growth by inhibiting the STIP1/AHCY/LDHA axis. In brief. Jin et al. demonstrated that targeting STIP1 can significantly inhibit the progression of esophageal squamous cell carcinoma. The high expression of STIP1 increased the interaction between AHCY and LDHA and then AHCY recruits PRMT3 to ...
Guoguo Jin, Yanming Song, Mingyang Yan, Shaobo Fang, Yang Shao, Kexin Zhao, Meng Liu, Qinxin Guo, Xinyang Jia, Chengjuan Zhang, Zhenwei Wang, Kangdong Liu, Xiang Li, Simin Zhao, Mee‐Hyun Lee, Zhiping Guo, Zigang Dong   +16 more
wiley   +1 more source

Circadian Clocks Function in Concert with Heat Shock Organizing Protein to Modulate Mutant Huntingtin Aggregation and Toxicity

Cell Reports, 2019
Summary: Neurodegenerative diseases commonly involve the disruption of circadian rhythms. Studies indicate that mutant Huntingtin (mHtt), the cause of Huntington’s disease (HD), disrupts circadian rhythms often before motor symptoms are evident.
Fangke Xu, Elzbieta Kula-Eversole, Marta Iwanaszko, Alan L. Hutchison, Aaron Dinner, Ravi Allada   +5 more
doaj  

The brain, circadian rhythms, and clock genes [PDF]

, 1998
Michael H. Hastings
openalex   +1 more source

Gut Microbiota‐Associated Metabolites Affected the Susceptibility to Heart Health Abnormality in Young Migrants at High‐Altitude

Exploration, EarlyView.
Long‐term migration to high‐altitude areas can readily result in chronic high‐altitude diseases; however, effective prevention and treatment methods are currently lacking. This study employed a multi‐omics approach, integrating metagenomics and metabolomics, to discover and validate that the decreased abundance of Veillonella rogosae, Streptococcus ...
Yongqiang Zhou, Zhexin Ni, Jingjing Liu, Dezhi Sun, Pan Shen, Xi Chen, Gaofu Li, Zhijie Bai, Yangyi Hu, Ningning Wang, Rui Wang, Lina Guan, Yihao Wang, Xianglin Tang, Yungang Lu, Baokun He, Haitao Lu, Wei Zhou, Yue Gao   +18 more
wiley   +1 more source

Puerariae lobatae Radix Alleviates Alcoholic Liver Injury by Regulating Circadian Rhythm and Intestinal Flora

Food Frontiers, EarlyView.
(A) PLR contains a variety of isoflavones; (B) PLR attenuated alcoholic liver injury; (C) PLR improved intestinal flora dysbiosis; (D) PLR regulated circadian rhythm. ABSTRACT This study used Puerariae lobatae Radix (PLR) to explore its improvement mechanism in mice with alcoholic liver injury from the perspective of intestinal flora and transcriptome.
Yanfang Liao, Jiajing Guo, Zhipeng Gao, Zhaoping Pan, Mingfang Peng, Yanjiao Fu, Fuhua Fu, Yang Shan   +7 more
wiley   +1 more source

An investigation into the transcription factors and regulatory mechanisms of Aspergillus

Food Safety and Health, Volume 3, Issue 3, Page 282-299, July 2025.
Foodborne pathogen Aspergillus, a prevalent etiologic agent among filamentous fungi, are distinguished by a significant repertoire of transcription factors encoded within their genomes. These regulatory proteins are instrumental in orchestrating key biological processes, including cellular growth, secondary metabolite biosynthesis, mycotoxin production,
Yuxin Qin, Huawei Yu, Jun Tian
wiley   +1 more source

Serotonergic phase shifts of the mammalian circadian clock: effects of tetrodotoxin and high Mg2+

, 1992
Rebecca A. Prosser, H. Craig Heller, Joseph D. Miller   +2 more
openalex   +1 more source

A circadian clock regulates the pH of the fish retina [PDF]

, 2000
Andrey V. Dmitriev, Stuart C. Mangel
openalex   +1 more source

Mutagenesis and Mapping of a Mouse Gene, Clock , Essential for Circadian Behavior

, 1994
Martha Hotz Vitaterna, David P. King, Anne-Marie Chang, Jon M. Kornhauser, Phillip L. Lowrey, J. David McDonald, William F. Dove, Lawrence H. Pinto, Fred W. Turek, Joseph S. Takahashi   +9 more
openalex   +2 more sources

Progress of non‐motor symptoms in early‐onset Parkinson's disease

Ibrain, EarlyView.
This study reviews the research progress related to non‐motor symptoms (NMS) in patients with early onset Parkinson's disease (EOPD), including neuropsychiatric symptoms, autonomic dysfunction, sleep disorders, and sensory disorders and also summarizes the characteristics of NMS in the genetic form of Parkinson's disease (PD).
Fanshi Zhang, Aidi Luo, Shusheng Liao, Mei Liu, Jun Zhang, Zucai Xu   +5 more
wiley   +1 more source