Results 191 to 200 of about 109,508 (306)

Immediate nuclear accumulation of BMAL1 to regulate cellular circadian clock synchronization. [PDF]

Commun Biol
Tamaru T, Kawamura G, Yoshitane H, Koinuma S, Fukada Y, Naito A, Ozawa T, Takamatsu K.   +7 more
europepmc   +1 more source

Neurodevelopmental assessment at 24 months in infants with esophageal atresia: A prospective cohort study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objective To evaluate neurodevelopment at 24 months in infants surgically treated for esophageal atresia (EA), using the ages and stages questionnaire (ASQ), and identify perinatal and early‐life factors associated with developmental delay. Methods Infants with EA were prospectively enrolled in a structured multidisciplinary follow‐up program.
Julia Tagmouti, Manon Midavaine, Victor Sartorius, Nicolas Vinit, Elise Leroy‐Terquem, Sylvie Beaudoin, Elsa Kermorvant‐Duchemin, Véronique Rousseau, Alexandre Lapillonne   +8 more
wiley   +1 more source

Circadian Clock Genes in Colorectal Cancer: From Molecular Mechanisms to Chronotherapeutic Applications. [PDF]

Biomedicines
Wang H, Zhou J, Pang S, Mei Y, Li G, Jin Y, Lin R.   +6 more
europepmc   +1 more source

Early life abuse and neglect in breast cancer survivors: Associations with physical and psychological health throughout diagnosis and survivorship

Journal of Traumatic Stress, EarlyView.
Abstract Childhood abuse and neglect worsen physical and mental health through adulthood. This study examined how childhood adversity affected physical and psychological symptoms associated with breast cancer treatment and survivorship at three points within the cancer trajectory. Breast cancer survivors (N = 209) were recruited following diagnosis and
Sonal K. Johal, M. Rosie Shrout, Annelise A. Madison, Stephanie J. Wilson, Stephen P. Povoski, William E. Carson III, Janice K. Kiecolt‐Glaser, Megan E. Renna   +7 more
wiley   +1 more source

The diverse roles of the circadian clock in cancer. [PDF]

Nat Cancer
Fortin BM, Mahieu AL, Fellows RC, Kang Y, Lewis AN, Ead AS, Lamia KA, Cao Y, Pannunzio NR, Masri S.   +9 more
europepmc   +1 more source

Deep learning of wrist accelerometry from UK Biobank data identifies early movement signatures of knee osteoarthritis up to 5 years before diagnosis

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aims to test whether week‐long wrist accelerometry combined with deep learning can (i) distinguish healthy individuals from people with knee osteoarthritis (KOA), (ii) separate prodromal KOA from established KOA, and (iii) identify individuals who will receive a KOA diagnosis within 5 years.
Ricardo Smits Serena, Michael T Hirschmann, Georg Matziolis, Rüdiger von Eisenhart‐Rothe, Daniel Rueckert, Florian Hinterwimmer, Christina Valle   +6 more
wiley   +1 more source

6-4 photolyase differentially modulates transcription in the vertebrate circadian clock. [PDF]

PLoS Genet
Li H, Scheitle C, Hu X, Kaiber JJ, Todo T, Vallone D, Fischer R, Foulkes NS.   +7 more
europepmc   +1 more source

Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer

Medicine Bulletin, EarlyView.
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei, Yunli Xu, Tianjiao Zhang, Shuyu Xu, Haonan Wang, Yuan Wang, Xinxin Xie, Xiaolong Liang   +7 more
wiley   +1 more source

Hypotensive Episodes Precede Cognitive Fluctuations in Parkinson's Disease Dementia

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Cognitive fluctuations (CFs) are a disabling feature in Parkinson's disease dementia (PDD) and contribute to caregiver burden. The relationship between CFs and neurogenic orthostatic hypotension (nOH), a common autonomic complication in PDD, has not been adequately examined.
Jorge Patino, Kevin Duque, Jesus Abanto, Aaron Bloemer, Heba Deraz, Alberto J. Espay, Abhimanyu Mahajan   +6 more
wiley   +1 more source

A role for the cholinergic neuron circadian clock in RNA metabolism and mediating neurodegeneration. [PDF]

Life Sci Alliance
Tam SB, Waldeck NJ, Wright M, Mojsilovic-Petrovic J, Baker EM, Kiskinis E, Bass J, Kalb RG.   +7 more
europepmc   +1 more source