Results 221 to 230 of about 301,259 (301)

Association Between Toilet Training Timing and Prognosis of Nocturnal Enuresis in Children: A Retrospective Study

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Toilet training (TT) is a critical developmental milestone with potential implications for lower urinary tract function. However, its association with the prognosis of nocturnal enuresis (NE) remains unclear. We aimed to evaluate whether the timing of TT initiation and completion affects 1‐year treatment outcomes in children with NE ...
Shota Endo, Hirokazu Ikeda, Yuma Iwanaka, Takahiro Ono, Chisato Oyake, Yuta Onuki, Yoshitaka Watanabe, Masaki Fuyama, Tsuneki Watanabe   +8 more
wiley   +1 more source

Circadian Clock Interaction with HIF1α Mediates Oxygenic Metabolism and Anaerobic Glycolysis in Skeletal Muscle. [PDF]

Cell Metab
Peek CB, Levine DC, Cedernaes J, Taguchi A, Kobayashi Y, Tsai SJ, Bonar NA, McNulty MR, Ramsey KM, Bass J.   +9 more
europepmc   +1 more source

Current status and future perspectives of platelet function‐guided precision antiplatelet therapy for patients with cerebral infarction

Neuroprotection, EarlyView.
Antiplatelet agents target the cyclooxygenase‐1 (COX‐1)/thromboxane A2 (TXA2) and adenosine diphosphate (ADP)‐P2Y12 (cytochrome P450 2C19 [CYP2C19]‐metabolized) platelet activation pathways, resulting in either drug resistance or over‐inhibition. The individualized therapeutic window balances ischemic risk (triggered by high on‐treatment platelet ...
Guoliang Zhu, Xiaoling Chen, Xinyi Huang, Quandan Tan, Qing Cao, Yali Yang, Yapeng Lin, Jie Yang   +7 more
wiley   +1 more source

Ginsenosides alleviate the progression of hepatic fibrosis by targeting the liver circadian clock gene <i>CLOCK</i>. [PDF]

Mol Med Rep
Yu J, Qian C, Que R, Zhou Y.
europepmc   +1 more source

Atopic dermatitis and attention‐deficit/hyperactivity disorder comorbidity in children and adolescents: Epidemiology, mechanisms, and clinical management

Pediatric Investigation, EarlyView.
This review synthesizes epidemiological evidence linking atopic dermatitis to attention‐deficit/hyperactivity disorder in children, proposes an “inflammation‐itch‐neurobehavioral axis” integrating sleep disruption, neuroendocrine dysregulation, and emerging neuro‐immune circuits, and outlines multidisciplinary management strategies targeting both skin ...
Qingyang Zhao, Yuan Liang, Ying Liu, Chunping Shen, Mutong Zhao, Jing Tian, Lei Jiao, Jing Sun, Ying Gu, Qiong Wu, Shan Wang, Lin Ma   +11 more
wiley   +1 more source

The Ontogeny of Rhythms in Circadian Clock Gene Expression in Mouse Brain and Neuroimmune Tissues. [PDF]

J Biol Rhythms
Bell KS, Chen R, Weitzner AS, Fonken LK.
europepmc   +1 more source

Quantifying Data Reuse in Proteomics Using PRIDE Downloads Statistics and a Semi‐Supervised LLM‐Based Framework

PROTEOMICS, EarlyView.
ABSTRACT Understanding how scientific datasets are accessed and reused is essential for resource planning and impact assessment. Here we present the PRIDE Archive download tracking infrastructure and a comprehensive analysis of 159.3 million download records from the PRIDE proteomics database (2021–2025), spanning 35,528 datasets accessed from 235 ...
Suresh Hewapathirana, Jingwen Bai, Chakradhar Bandla, Selvakumar Kamatchinathan, Deepti J. Kundu, Nithu Sara John, Boma Brown‐Harry, Nandana Madhusoodanan, Joan Marc Riera Duocastella, Juan Antonio Vizcaíno, Yasset Perez‐Riverol   +10 more
wiley   +1 more source

Photic Phase Shifts of the Mouse Circadian Clock Are Defined by Scene Irradiance Across Differences in the Spatial Distribution of Light. [PDF]

Clocks Sleep
Huang Q, Martial FP, Storchi R, Lucas RJ.   +3 more
europepmc   +1 more source

Evolution of photoperiod insensitivity drove the westward expansion of broomcorn millet

PLANTS, PEOPLE, PLANET, EarlyView.
This research highlights how ancient farming communities adapted crops to challenging environments, enabling the spread of agriculture across Eurasia. By demonstrating that broomcorn millet evolved reduced sensitivity to day‐length, the study explains how this crop could support food production in regions with short growing seasons and long summer days.
Giedre Motuzaite Matuzeviciute, Michael Kempf, Margaux L. C. Depaermentier, Harriet Hunt, Kristina Jaskune   +4 more
wiley   +1 more source

Diurnal Regulation of Hippocampal Synaptic Plasticity in Aged Rats and the Role of the Circadian Clock Gene Per1. [PDF]

Hippocampus
Ralph LT, Kang S, Joe LA, Tidball P, Israwi AR, Tian M, Kadia A, Zhang L, Jin F, Ingram R, Bortolotto ZA, Lightman SL, Conway-Campbell BL, Nash JE, Robertson J, Bradley CA, Gertsenstein M, Nutter LMJ, Georgiou J, Collingridge GL.   +19 more
europepmc   +1 more source