Results 201 to 210 of about 5,427 (264)

A walk in the park—Identifying healthy greenspaces using scents

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
As urbanisation accelerates globally, access to nature is increasingly recognised as vital for public health and wellbeing. We captured and analysed plant‐emitted airborne ‘scent signatures’ across Oxford's urban greenspaces to assess their potential health relevance.
William T. Kay   +6 more
wiley   +1 more source

Combining radiotherapy with CAR‐T cell therapy for solid tumors: Challenges, mechanisms, and future directions

open access: yesPrecision Radiation Oncology, EarlyView.
Radiotherapy enhances CAR‐Tcell therapy by increasing antigenicity, improving trafficking, and reshaping the tumor microenvironment. Despite its dual effects, including potential immune suppression, understanding these mechanisms enables the development of strategies to maximize synergy in solid tumors.
Leran Qiu   +4 more
wiley   +1 more source

Larval antibiosis to cabbage stem flea beetle (Psylliodes chrysocephala) is absent within oilseed rape (Brassica napus)

open access: yesPest Management Science, EarlyView.
We screened a panel of 98 Brassicaceae genotypes (97 Brassica napus and 1 Sinapis alba) for cabbage stem flea beetle (Psylliodes chrysocephala) larval antibiosis. We found limited evidence for antibiosis across B. napus but consistent antibiosis in S. alba. Brassicaceae relatives may therefore better inform resistance traits for breeding.
Ryan E Brock   +3 more
wiley   +1 more source

Synergistic transition from type‐I‐like to type‐II‐like symptomology in a pyrethroid mixture and its impact on knockdown–mortality relationships in Musca domestica L

open access: yesPest Management Science, EarlyView.
In the present study, relationship between knockdown and mortality of insecticides was examined against the adult female housefly, Musca domestica. Type‐I pyrethroid insecticides showed a weak linkage, as early knocked down flies did not always result in mortality, while type‐II pyrethroids and organophosphates exhibited strong correlation between the ...
Junho Yoon, Jun‐Hyung Tak
wiley   +1 more source

Effects of timed LED regimes on tomato plant traits, performance of two‐spotted spider mites, and predatory mites (Phytoseiulus persimilis)

open access: yesPest Management Science, Volume 81, Issue 4, Page 2300-2311, April 2025.
Light‐emitting diode (LED)‐based treatments for enhancing crop production and pest management have primarily focused on continuous treatments. This study, using Tetranychus urticae and Phytoseiulus persimilis, demonstrates that the timing of LED supplementation is crucial for designing integrated pest management strategies that improve both plant ...
Patrice Savi   +5 more
wiley   +1 more source

Physiologically based pharmacokinetic modeling and simulation of topiramate in populations with renal and hepatic impairment and considerations for drug–drug interactions

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 510-522, March 2025.
Abstract Topiramate (TPM) is a broad‐spectrum antiepileptic drug (AED) commonly prescribed for approved and off‐label uses. Routine monitoring is suggested for clinical usage of TPM in special population due to its broad side effect profile. Therefore, it is crucial to further explore its pharmacokinetic characteristics.
Shuqing Chen   +6 more
wiley   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

Disrupted joint clock is associated with rhythmic expression of bone destruction factors in collagen‐induced arthritis

open access: yesRheumatology &Autoimmunity, EarlyView.
Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang   +7 more
wiley   +1 more source

Cameras do not always take a full picture: wolf activity patterns revealed by accelerometers versus road‐positioned camera traps

open access: yesRemote Sensing in Ecology and Conservation, EarlyView.
Camera traps have become an increasingly popular non‐invasive alternative to animal‐attached devices for studying wildlife behaviour. This study compared wolf (Canis lupus) activity patterns derived from collar accelerometers and road‐positioned camera traps and revealed strong overall agreement but also important seasonal and diel mismatches between ...
Katarzyna Bojarska   +7 more
wiley   +1 more source

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