Results 131 to 140 of about 492,257 (392)
Circadian Rhythms in Immunity [PDF]
Current Allergy and Asthma Reports, 2020 This review is focused on the existing evidence for circadian control of innate and adaptive immune responses to provide a framework for evaluating the contributions of diurnal rhythms to control of infections and pathogenesis of disease.Circadian rhythms driven by cell-autonomous biological clocks are central to innate and adaptive immune responses ...
openaire +3 more sources
A Subcircuit in the Suprachiasmatic Nucleus Generates Wakefulness
Advanced Science, EarlyView.This study identifies a sub‐circuit within the circadian pacemaker suprachiasmatic nucleus (SCN) that promotes arousal. This sub‐circuit is labeled by the clock output molecule mWAKE, which suppresses its excitability in a time‐dependent manner. mWAKE‐expressing cells in the SCN (SCNmWAKE cells) project to the subparaventricular zone (SPZ) to mediate ...
Qiang Liu +6 more
wiley +1 more source
The Possible Role of Extra-ocular Photoreceptors in the Entrainment of Lobster Circadian Rhythms to Light:Dark Cycles [PDF]
, 2013 The American lobster, Homarus americanus, is a decapod crustacean whose daily nocturnal rhythms of activity are driven, in part, by an internal biological clock. While this circadian clock is capable of producing a rhythm of approximately 24 hours on its
McKinney, Sara A
core +1 more source
Neurocardiovascular deficits in the Q175 mouse model of Huntington's disease. [PDF]
, 2017 Cardiovascular dysautonomia as well as the deterioration of circadian rhythms are among the earliest detectable pathophysiological changes in individuals with Huntington's disease (HD). Preclinical research requires mouse models that recapitulate disease
Colwell, Christopher S +7 more
core +1 more source
Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis
Advanced Science, EarlyView.This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu +9 more
wiley +1 more source
Circadian Rhythm, Lifestyle and Health: A Narrative Review
Iranian Journal of Public Health, 2018 Background: The circadian rhythm regulation plays a crucial role in people`s healthy lives affected by factors consisting of cosmic events related to the universe and earth, environmental factors (light, night and day duration, seasons) and lifestyles ...
Dariush FARHUD, Zahra ARYAN
doaj
Melatonin receptor expression in the zebra finch brain and peripheral tissues [PDF]
, 2012 The circadian endocrine hormone melatonin plays a significant role in many physiological processes such as modulating sleep/wake cycle and oxidative stress.
Brandstaetter, Roland +2 more
core +1 more source
Biohybrid Computing with Proteinoids and Algae
Advanced Science, EarlyView.We developed a novel biohybrid computing system by combining proteinoid microspheres with algae. The biological mixture creates spontaneous electrical oscillations. These oscillations can perform simple logic operations, such as AND, OR, NAND, and NOR gates. Environmental factors like temperature and pH affect how the system works.
Panagiotis Mougkogiannis +1 more
wiley +1 more source
Analysis of DNA-Damage Response to ionizing radiation in serum-shock synchronized human fibroblasts. [PDF]
, 2017 Many aspects of cellular physiology, including cellular response to genotoxic stress, are related to the circadian rhythmicity induced by the molecular clock.
Barbieri, Vito +4 more
core +1 more source
Aβ-induced degradation of BMAL1 and CBP leads to circadian rhythm disruption in Alzheimer’s disease
Molecular Neurodegeneration, 2015 Patients with Alzheimer’s disease (AD) frequently experience disruption of their circadian rhythms, but whether and how circadian clock molecules are perturbed by AD remains unknown. AD is an age-related neurological disorder and amyloid-β (Aβ) is one of
Hyundong Song +8 more
semanticscholar +1 more source