Results 131 to 140 of about 125,855 (308)

Genetic and Environmental Associations Among Pain, Sleep Disturbances, and Substance Use Intent in Early Adolescence

open access: yesJournal of Adolescence, EarlyView.
ABSTRACT Purpose Pain, sleep disturbances, and substance use are common in adolescence, with research indicating that genetic and environmental factors account for variation in each of these behavioral and health outcomes. Moreover, pain, sleep disturbances, and substance use often co‐occur during adolescence. However, research has not examined whether
Kit K. Elam   +4 more
wiley   +1 more source

Effects of 1267 nm Illumination on Microcirculation Regulatory Mechanisms

open access: yesJournal of Biophotonics, EarlyView.
The question of activation of blood flow regulatory mechanisms during laser illumination remains open to date. This study showed the effect of laser exposure on the microcirculatory bed, which appears in the form of endothelium‐dependent vascular activity.
Lyubov Eratova   +2 more
wiley   +1 more source

Saliva as a TDM matrix and its application in the model‐informed precision dosing

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract This study reviews the main points of saliva as a therapeutic drug monitoring (TDM) matrix, its advantages and limitations, the methods of saliva sample collection and testing, the types of drugs in saliva TDM, and the methods of establishing saliva population pharmacokinetic (Pop PK) models, as well as summarizes the experiences and ...
Baohua Xu   +9 more
wiley   +1 more source

DESYNCHRONIZATION OF HUMAN CIRCADIAN RHYTHMS

open access: bronze, 1967
Jürgen Aschoff   +2 more
openalex   +2 more sources

Exogenous Melatonin and Sleep Quality: A Scoping Review of Systematic Reviews

open access: yesThe Journal of Clinical Pharmacology, EarlyView.
Abstract Melatonin is increasingly used to treat sleep disturbances, yet its overall efficacy remains unclear due to variability in existing evidence. This scoping review aimed to synthesize systematic reviews with meta‐analyses assessing the effects of exogenously administered melatonin on sleep quality in humans.
Samyuktha Iyer   +3 more
wiley   +1 more source

Genetic and environmental influences on sleep quality, ability to settle, and crying duration in 2‐ and 5‐month‐old infants: A longitudinal twin study

open access: yesJCPP Advances, EarlyView.
This study found that genetic factors largely influence crying duration and settle ability in infancy, while shared environmental factors primarily affect the number of night wakeups. Etiological influences tended to change from 2 to 5 months, reflecting a highly plastic period in infant brain development and in child‐environment interactions. Abstract
Charlotte Viktorsson   +5 more
wiley   +1 more source

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