Results 181 to 190 of about 93,323 (251)

Red blood cell membrane proteome as a reporter of disease severity, transfusion impact and genetic background in transfusion‐dependent β‐thalassaemia

British Journal of Haematology, EarlyView.
Summary Omics technologies have transformed research in haemoglobinopathies, yet the proteome of RBCs remains largely unexplored in transfusion‐dependent thalassaemia (TDT). In this proteomic analysis, Red blood cell (RBC) membranes from 48 adults with TDT were compared with healthy controls.
Konstantina Theocharaki, Sophia Delicou, Aikaterini Ntzoura‐Kani, Nikolaos Simantiris, Marianna Politou, Veroniki Komninaka, Martina Samiotaki, Jerome Zoidakis, Marianna H. Antonelou   +8 more
wiley   +1 more source

From barriers to benefits: A personalized sleep intervention enhances sleep duration and emotional health in chronic short sleepers

British Journal of Psychology, EarlyView.
Abstract This pilot study evaluated a personalized sleep intervention incorporating motivational interviewing techniques to address sleep barriers, along with tailored sleep hygiene and extension for chronic short sleepers. Eleven university students completed a 14‐day sequential intervention (baseline, sleep hygiene and a combined phase adding 90‐min ...
Wei Wang, Ho Yin Derek Ma, Ming Ming Chiu, Shu Fai Cheung, C. Harry Hui, Mark Lawrence Wong, Janet Hui‐wen Hsiao, Rong Wei Sun, Yeuk Ching Lam, Akira Basa Okabe, Chin Ho Chan, Esther Yuet Ying Lau   +11 more
wiley   +1 more source

Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation?

British Journal of Pharmacology, EarlyView.
Psychedelic drugs that activate 5‐HT2A receptors have been long used for cultural, medicinal and recreational purposes. Interest in psychedelics for treating psychiatric disorders has resurged recently and is well documented; less well recognised are their anti‐inflammatory properties. Growing evidence now demonstrates that psychedelics modulate immune
Omar Qureshi, Jamie Cowley, Ashley Pegg, Alison J. Cooper, John Gordon, Catherine A. Brady, Antonio Belli, Sam Butterworth, Rachel Upthegrove, Nick Andrews, Nicholas M. Barnes   +10 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

Clinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton, Myrte Schoenmakers, Brenda W. J. H. Penninx, Mariëtte R. Boon, Elisabeth F. C. van Rossum   +4 more
wiley   +1 more source

Short‐term effects of wildlife rehabilitation disappear over time in the wild: A case study on Spanish imperial eagles

Conservation Science and Practice, EarlyView.
We assessed the effectiveness of Wildlife Recovery Centers by comparing dispersal behavior of rehabilitated and wild Spanish imperial eagles using GPS tracking. Rehabilitated individuals initially moved shorter distances, rested more, and hunted less than wild controls, but these differences declined over time and ultimately disappeared.
Unai Ormazabal‐Santa Cruz, José M. Abad‐Gómez, Manuel Parejo, José M. Guzmán‐Bolaños, María Arredondo, María Jesús Palacios, Ángel Sánchez, Álvaro Guerrero, Cosme López‐Calderón   +8 more
wiley   +1 more source

Circadian variation of the atropine effect on the running performance of mice treated with 1,2,2-trimethylpropylmethylphosphonofluoridate (soman) [PDF]

, 1987
Arbogast, B., Arbogast, Helmut, Hallek, M., Hildebrandt, Gunther, Szinicz, L.   +4 more
core  

Sleep Efficiency Predicts Next‐Day Glycaemia and Daytime Glycaemia Influences Sleep in Free‐Living Adults at Risk of Type 2 Diabetes

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aim To investigate how sleep features influence next‐day diurnal glucose homeostasis and vice versa in free‐living adults at risk of type 2 diabetes. Materials and Methods This observational repeated‐measures study included 388 adults aged 25–65 years (50% women) with overweight or obesity (BMI ≥ 25.0–< 40.0 kg/m2).
Antonio Clavero‐Jimeno, Juan J. Martin‐Olmedo, Jairo H. Migueles, Alba Camacho‐Cardenosa, Marcos Molina‐Fernandez, Manuel Dote‐Montero, Jordi Merino, Manuel Muñoz‐Torres, Idoia Labayen, Jonatan R. Ruiz   +9 more
wiley   +1 more source

Photoperiod‐Regulated Thermal Tolerance of the Non‐Diapausing Insect Ceratitis capitata (Diptera: Tephritidae)

Entomologia Experimentalis et Applicata, EarlyView.
Developmental photoperiodic exposure (photoacclimation) from egg to adult emergence alters thermal tolerance in Ceratitis capitata. Flies reared under contrasting photoperiods (0:24, 8:16, 14:10, and 24:0 L:D) showed significant shifts in both CTmin and CTmax, whereas adult‐only photoacclimation affected CTmax but not CTmin.
Antonis G. Papadopoulos, Nikos T. Papadopoulos   +1 more
wiley   +1 more source

Diurnal and nocturnal salivary fluoride bioavailability following brushing with high‐ or regular‐fluoride dentifrices

European Journal of Oral Sciences, EarlyView.
Abstract This study evaluated salivary fluoride (F) bioavailability during diurnal and nocturnal periods after using a high‐fluoride or regular dentifrice. Fifteen healthy adults participated in a double‐blind crossover study, brushing with either a 1450 ppm F or 5000 ppm F dentifrice.
Guereth Carvalho, Guilherme Santana, Niciane Macena, Gláuber Vale   +3 more
wiley   +1 more source