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Disorders of sleep and circadian rhythms

2018
Sleep is fundamental to the survival of humans. However, knowledge regarding the role of sleep and its regulation is poorly understood. Genetics in flies, mice, and humans has led to a detailed understanding of some aspects of circadian regulation. Sleep homeostasis (the effect of increasing periods of wakefulness on our sleep propensity) is largely ...
Ying-Hui Fu   +3 more
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Circadian rhythm sleep disorders

Current Treatment Options in Neurology, 1999
Delayed sleep phase syndrome (DSPS) is best treated by first using behaviorally scheduled sleeping and arising times to realign the patient's sleep-wake cycle to local time and then by keeping the cycle in synchrony with local time by adherence to a strict daily schedule. Adjunct treatment with morning light exposure or evening melatonin may be useful,
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Circadian Rhythm Disorders in Pediatrics

Pediatric Annals, 2008
<P>Juan is a 14-year-old high school freshman who falls asleep throughout the morning at his desk. By afternoon he is awake and functioning well. His grades are dropping. He sleeps through several of his most important classes. Juan’s mother is concerned because he takes up to 4 hours to fall asleep on weeknights, finally sleeping at about 1 a.m.
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Circadian Rhythms and Psychiatric Disorders in the Elderly

Journal of Geriatric Psychiatry and Neurology, 1996
This article reviews changes in circadian rhythms that have been reported to occur in the elderly psychiatric population. Data relating to circadian changes in normal aging are included where relevant. Information was obtained from: (1) a computerized MEDLINE search from 1975 to May 1996; (2) a review of bibliographies of papers obtained through the ...
Colin M. Shapiro   +3 more
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Circadian Rhythm Disorders

2007
Simply stated, everyday people should strive to fall asleep at the time when they are sleepiest. For most people this means having the major sleep period start in the evening and conclude at dawn. However, situations arise in which a person’s sleep timing, or circadian rhythm of sleep, is not synchronized with other factors, potentially leading to ...
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Is Seasonal Affective Disorder a Disorder of Circadian Rhythms?

CNS Spectrums, 2001
AbstractSeasonal affective disorder (SAD) is a form of depression that starts in the fall and ends in the spring. This article reviews existing theories about the relationship between circadian rhythms and the disorder. Recent research indicates that as with pharmacologic antidepressants, at least 2–4 weeks are needed to demonstrate the effectiveness ...
Dan A. Oren, Paul H. Desan
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Sleep and circadian rhythm disorders

2020
This chapter reviews the most common sleep disorders in older adults and their treatment. It begins with a brief review of sleep physiology and then gives an outline on how to take a comprehensive sleep history. There are physiological sleep changes related to ageing, but sleep disorders are not part of normal ageing and are often associated with ...
Kirstie Anderson   +3 more
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Circadian Rhythms in Affective Disorders

2001
The affective or mood disorders are among the most common psychiatric conditions. They cause considerable morbidity and mortality, and therefore have received a great deal of research attention. For reasons which will be described below, researchers with an interest in circadian rhythms have been among those working to understand the pathophysiology ...
Ellen Leibenluft, Ellen Frank
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Genetics of Circadian Rhythm Disorders

Sleep Medicine Clinics, 2011
The circadian timing system is ubiquitous to nearly all organisms on earth. The 24-hour cycle of light/ dark exhibited by the solar day is reflected in a myriad of circadian rhythms in many living organisms. External environmental changes in the 24-hour day synchronize the various physiologic, biochemical, and behavioral processes in a predictable ...
Anne Marie Chang   +2 more
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Circadian Rhythm Sleep-Wake Disorders

Psychiatric Clinics of North America, 2015
The circadian system regulates the timing and expression of nearly all biological processes, most notably, the sleep-wake cycle, and disruption of this system can result in adverse effects on both physical and mental health. The circadian rhythm sleep-wake disorders (CRSWDs) consist of 5 disorders that are due primarily to pathology of the circadian ...
Phyllis C. Zee   +2 more
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