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Circadian Rhythm Sleep Disorders
Clinics in Chest Medicine, 2010Because there is insufficient cellular energy for organisms to perform their functions at the same constant rate and at the same time, all biologic processes show rhythmicity, each with its own unique frequency, amplitude, and phase. Optimal sleep and wakefulness requires proper timing and alignment of desired sleep-wake schedules and circadian rhythm ...
Naveen, Kanathur +2 more
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Circadian Rhythm Sleep Disorders
Primary Care: Clinics in Office Practice, 2005Individuals who have circadian rhythm sleep disorders present with symptoms of insomnia or excessive sleepiness and complain of an inability to sleep at their desired time. Although the primary etiology of these disorders is a misalignment between the endogenous circadian clock and the external environment, social and behavioral factors can also play ...
Kathryn J, Reid, Helen J, Burgess
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Circadian Rhythm Sleep Disorders
Chest, 2006Humans exhibit endogenous circadian rhythms that are regulated by the master circadian clock of the body, the suprachiasmatic nucleus. These endogenous circadian rhythms are aligned to the outside world by social and environmental cues. Circadian rhythm sleep disorders (CRSD) occur when there is an alteration of the internal timing mechanism or a ...
Brandon S, Lu, Phyllis C, Zee
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Circadian rhythms in neurodegenerative disorders
Nature Reviews Neurology, 2021Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the circadian rhythms that synchronize physiological and behavioural functions in humans. The circadian system influences most physiological processes, including sleep, alertness and cognitive performance. Disruption of circadian homeostasis has deleterious effects on human
Malik Nassan, Aleksandar Videnovic
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Circadian rhythm sleep disorders
Current Treatment Options in Neurology, 1999Delayed sleep phase syndrome (DSPS) is best treated by first using behaviorally scheduled sleeping and arising times to realign the patient's sleep-wake cycle to local time and then by keeping the cycle in synchrony with local time by adherence to a strict daily schedule. Adjunct treatment with morning light exposure or evening melatonin may be useful,
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2008
Abstract Rhythmicity in biological processes is a fundamental characteristic of life. There is simply insufficient cellular energy for organisms to perform all their functions at the same constant rate (steady state) and all at the same time.
Christopher D. Fahey, Phyllis C. Zee
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Abstract Rhythmicity in biological processes is a fundamental characteristic of life. There is simply insufficient cellular energy for organisms to perform all their functions at the same constant rate (steady state) and all at the same time.
Christopher D. Fahey, Phyllis C. Zee
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Abstract Circadian rhythms define the near-24-hour oscillations observed in physiological processes. Circadian rhythm disorders result when there is a misalignment between an individual’s physiological rhythm and the environment. This can result from an intrinsic inability to entrain with the external environment, or from environmental ...
Sabra M. Abbott +2 more
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Sabra M. Abbott +2 more
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Circadian Rhythm Sleep-Wake Disorders
Continuum, 2020This article provides an overview of circadian physiology and discusses common presentations and treatment strategies for the circadian rhythm sleep-wake disorders.Circadian rhythms are present throughout the body, and appreciation for the role that circadian dysregulation plays in overall health is increasing, with mounting associations between ...
Phyllis C, Zee, Sabra M, Abbott
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ACS Chemical Neuroscience, 2018
Glutamate, a primary excitatory neurotransmitter and an important intermediate in the cellular metabolism of the brain, has a widespread influence in the sleep-wake regulatory system. Glutamate transporters, including vesicular glutamate transporters and
Suifen He, Xiuping Zhang, Shaogang Qu
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Glutamate, a primary excitatory neurotransmitter and an important intermediate in the cellular metabolism of the brain, has a widespread influence in the sleep-wake regulatory system. Glutamate transporters, including vesicular glutamate transporters and
Suifen He, Xiuping Zhang, Shaogang Qu
semanticscholar +1 more source
Circadian Rhythms in Mood Disorders
2021Altered behavioral rhythms are a fundamental diagnostic feature of mood disorders. Patients report worse subjective sleep and objective measures confirm this, implicating a role for circadian rhythm disruptions in mood disorder pathophysiology. Molecular clock gene mutations are associated with increased risk of mood disorder diagnosis and/or severity ...
Madeline R, Scott, Colleen A, McClung
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