This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina+15 more
wiley +1 more source
Circadian rhythms and hormonal homeostasis: Pathophysiological implications [PDF]
Over recent years, a deeper comprehension of the molecular mechanisms that control biological clocks and circadian rhythms has been achieved. In fact, many studies have contributed to unravelling the importance of the molecular clock for the regulation ...
Bruscalupi, Giovannella, Gnocchi, Davide
core +2 more sources
Nano‐biosensors offer real‐time monitoring of cognitive and emotional states through biomarkers like cortisol and dopamine. They enhance personalized learning, mental health interventions, and daily performance across sectors. Integrated into wearables and IoT, they promise a transformative impact while raising ethical, technological, and regulatory ...
Priscilla Adomako Gyasi+6 more
wiley +1 more source
Сontribution of circadian rhythms to the development of neurological disorders after prolonged anesthesia [PDF]
Despite the improvement of pre-, intra- and postoperative care methods, the problem of the development of postoperative neurological complications following prolonged anesthesia remains.
Nikita A. Mazurov+5 more
doaj +1 more source
Extreme morning chronotypes are often familial and not exceedingly rare: the estimated prevalence of advanced sleep phase, familial advanced sleep phase, and advanced sleep-wake phase disorder in a sleep clinic population. [PDF]
Study objectivesReport the first prevalence estimates of advanced sleep phase (ASP), familial advanced sleep phase (FASP), and advanced sleep-wake phase disorder (ASWPD).
Ashbrook, Liza H+6 more
core
The Impact of Lighting Conditions on Users' Alertness and Working Memory in Confined Spaces
ABSTRACT Confined spaces, characterized by limited natural ventilation, the absence of windows, and restricted access to natural light, present distinct challenges. While most studies focus on lighting's effect on sleep, confined spaces are now more often used for short‐term work‐rest cycles, especially in office settings.
Zaoyi Sun+7 more
wiley +1 more source
Sleep and circadian rhythm disturbance in bipolar disorder
BackgroundSubjective reports of insomnia and hypersomnia are common in bipolar disorder (BD). It is unclear to what extent these relate to underlying circadian rhythm disturbance (CRD). In this study we aimed to objectively assess sleep and circadian rhythm in a cohort of patients with BD compared to matched controls.MethodForty-six patients with BD ...
Bradley AJ+7 more
openaire +6 more sources
The role of the mammalian prion protein in the control of sleep [PDF]
Sleep disruption is a prevalent clinical feature in many neurodegenerative disorders, including human prion diseases where it can be the defining dysfunction, as in the case of the “eponymous” fatal familial insomnia, or an early-stage symptom as in ...
Gill, Andrew C., Roguski, Amber
core +2 more sources
Circadian Gene BMAL1 Regulation of Cellular Senescence in Thyroid Aging
BMAL1 downregulation during aging reduces NFKBIA expression, accelerating thyroid cellular senescence and impairing hormone synthesis. Circadian rhythm disruption exacerbates thyroid functional decline, highlighting the BMAL1‐NFKBIA axis as a key mediator of aging‐related thyroid dysfunction and offering insights for stabilizing thyroid health in aging
Dandan Zong+4 more
wiley +1 more source
The relationship between sleep disorders and testosterone in men
Plasma testosterone levels display circadian variation, peaking during sleep, and reaching a nadir in the late afternoon, with a superimposed ultradian rhythm with pulses every 90 min reflecting the underlying rhythm of pulsatile luteinizing hormone (LH)
Gary Wittert
doaj +1 more source