Results 121 to 130 of about 63,496 (329)

Homo sapiens, industrialisation and the environmental mismatch hypothesis

open access: yesBiological Reviews, EarlyView.
ABSTRACT For the vast majority of the evolutionary history of Homo sapiens, a range of natural environments defined the parameters within which selection shaped human biology. Although human‐induced alterations to the terrestrial biosphere have been evident for over 10,000 years, the pace and scale of change has accelerated dramatically since the onset
Daniel P. Longman, Colin N. Shaw
wiley   +1 more source

Genetic contributions to circadian activity rhythm and sleep pattern phenotypes in pedigrees segregating for severe bipolar disorder [PDF]

open access: bronze, 2015
Lucia Pagani   +33 more
openalex   +1 more source

Analysis of Sociodemographic and Psychological Variables Involved in Sleep Quality in Nurses [PDF]

open access: yes, 2019
Background: Sleep quality is related to health and quality of life and can lead to the development of related disorders. This study analyzed the sociodemographic and psychological factors related to sleep quality in nurses.
Gázquez Linares, José Jesús   +3 more
core   +1 more source

Glucocorticoids and HPA axis regulation in the stress–obesity connection: A comprehensive overview of biological, physiological and behavioural dimensions

open access: yesClinical Obesity, Volume 15, Issue 2, April 2025.
Summary Chronic stress, characterized by increased long‐term exposure to the glucocorticoid hormone cortisol, is increasingly linked to obesity development. Still, various knowledge gaps persist, including on underlying pathophysiological mechanisms. The aim of the current review is to provide the latest insights on the connection between stress and ...
Robin Lengton   +4 more
wiley   +1 more source

Gestational Melatonin Supplementation Attenuates Maternal Sleep Deprivation‐Induced Steatohepatitis Susceptibility in Offspring

open access: yesCell Proliferation, EarlyView.
Maternal SD during pregnancy enhances the development of diet‐induced NASH in adult offspring of both sexes through an NR4A3‐dependent mechanism, characterised by heightened inflammation and increased apoptosis. Maternal melatonin supplementation effectively alleviates this increased susceptibility to NASH in offspring.
Fei Guo   +6 more
wiley   +1 more source

p75NTR Promotes Circadian‐Driven Mineralization During Tooth Development via CK2/PER2 Pathway

open access: yesCell Proliferation, EarlyView.
The diagram illustrates how the circadian rhythm regulates the p75NTR‐CK2‐PER2 axis, driving rhythmic biomineralisation during tooth development. ABSTRACT Circadian rhythm is an essential biological process that synchronises physiological activities with environmental light/dark cycles.
Manzhu Zhao   +8 more
wiley   +1 more source

Reallocating morning physical activity to later‐day activity and its association with type 2 diabetes incidence: The Maastricht Study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims The timing of physical activity may influence metabolic health through interactions with circadian rhythms, yet its role in type 2 diabetes mellitus (T2DM) development is unclear. We investigated associations between time‐of‐day‐specific physical activity and incident T2DM, and whether theoretically reallocating activity from morning to ...
Marvin Y. Chong   +8 more
wiley   +1 more source

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