Results 51 to 60 of about 52,083 (330)

Intestinal Clock Promotes Cognitive Memory Through Adenosine Signaling

Advanced Science, EarlyView.
The intestinal clock controls the expression of an adenosine enzyme that modulates systemic adenosine level and A1R signaling in the hippocampus, and in turn, cognitive function involving long‐term potentiation and BDNF‐dependent synaptic changes.
Min Chen, Fugui Zhang, Yifei Xiao, Xuejun Jiang, Zhiqian Yan, Jinyi Wang, Xiting Lv, Jialu Cui, Linna Ha, Hui Chen, Yongkang Dang, Zifei Qin, Jing Yang, Baojian Wu   +13 more
wiley   +1 more source

Circadian period and the timing of melatonin onset in men and women: Predictors of sleep during the weekend and in the laboratory [PDF]

, 2015
Sleep complaints and irregular sleep patterns, such as curtailed sleep during workdays and longer and later sleep during weekends, are common. It is often implied that differences in circadian period and in entrained phase contribute to these patterns ...
Archer, SN, Dijk, D-J, Hasan, S, Johnston, JD, Lazar, AS, Lo, JC-Y, Santhi, N, Schantz, MV   +7 more
core   +2 more sources

Сон в Антарктиде: от проблем с засыпанием до понимания проблем [PDF]

, 2020
From the fi rst expeditions, adaptation to the harsh environment of Antarctica, the expeditionists complained of a trouble sleeping. During a long stay on the continent, the polar explorers are exposed to a large number of extreme environmental factors ...
Бабийчук, Г.А., Луценко, Д.Г., Луценко, Е.Л., Моисеенко, Е.В., Шило, А.В.   +4 more
core   +1 more source

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones, Julie Park, Silothabo Dliso, Daniel B. Hawcutt, Alena Shantsila, Gregory Y. H. Lip, Joanne Blair   +6 more
wiley   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu, Xu Zhang, Waner Liu, Zhe Zhou, Siyu Xiong, Jie Li, Xiang Chen, Cong Peng   +7 more
wiley   +1 more source

MicroRNA: A Key Player for the Interplay of Circadian Rhythm Abnormalities, Sleep Disorders and Neurodegenerative Diseases

Clocks & Sleep, 2020
Circadian rhythms are endogenous 24-h oscillators that regulate the sleep/wake cycles and the timing of biological systems to optimize physiology and behavior for the environmental day/night cycles.
Chisato Kinoshita, Yayoi Okamoto, Koji Aoyama, Toshio Nakaki   +3 more
doaj   +1 more source

Plasticity of the intrinsic period of the human circadian timing system. [PDF]

PLoS ONE, 2007
Human expeditions to Mars will require adaptation to the 24.65-h Martian solar day-night cycle (sol), which is outside the range of entrainment of the human circadian pacemaker under lighting intensities to which astronauts are typically exposed. Failure
Frank A J L Scheer, Frank A J L Scheer, Kenneth P Wright, Richard E Kronauer, Charles A Czeisler   +4 more
doaj   +1 more source

Sleep and Circadian Rhythm Disturbances in Diabetes: A Narrative Review

Diabetes, Metabolic Syndrome and Obesity, 2022
Femke Rutters,1,2 Giesje Nefs3– 5 1Department of Epidemiology and Data Science, Amsterdam UMC, location VUmc, Amsterdam, the Netherlands; 2Amsterdam Public Health Research Institute, Amsterdam, the Netherlands; 3Department of Medical Psychology, Radboud ...
Rutters F, Nefs G
doaj  

Importance of regular lifestyle with daytime bright light exposure on circadian rhythm sleep–wake disorders in pervasive developmental disorders

Japanese Dental Science Review, 2011
Considerable attention has been paid to individuals showing social maladjustment as well as withdrawal from social situations and activity, a state referred to as “Hikikomori” in Japanese.
Nana N. Takasu, Motomi Toichi, Wataru Nakamura   +2 more
doaj   +1 more source

Mental health, sleep quality, and hormonal circadian rhythms in pregnant women with threatened preterm labor: a prospective observational study

BMC Pregnancy and Childbirth, 2023
Background Threatened preterm labor (TPL) is an important obstetrical challenge. Pregnant women with TPL may develop psychological and physical problems such as mental health disorders, sleep disturbance, and hormonal circadian rhythm disruption.
Xiao-Juan Wang, Xiao-Ting Li, Na Chen, Long Huang, Shui-Xiu Huang, Ting-Ting Chen, Gui-Hua Liu, Rong-Fang Hu   +7 more
doaj   +1 more source