Results 151 to 160 of about 1,017,685 (293)

Cross-paradigm audit of large language model judges for clinical text evaluation. [PDF]

NPJ Digit Med
Pakull TMG, Warmer S, Arzideh K, Hilser T, Hosters B, Damm H, Nensa F, Schuler M, Borys K, Horn PA, Hosch R, Friedrich CM.   +11 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Unstable Pulmonary Artery Pseudoaneurysm in Hughes-Stovin Syndrome: A Life-Threatening Contained Rupture That Requires Immediate Endovascular Management. [PDF]

Open Respir Arch
Emad Y, Ragab Y, Ten Klooster PM, Rasker JJ, Hughes–Stovin Syndrome International Study Group (HSSISG).   +4 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Interactive Effects of Executive Function and Language Ability on Children's Cross-Situational Word Learning. [PDF]

J Speech Lang Hear Res
Crespo K, Khandelwal M, Rushi G.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Medical Staff Circle photo

Black and white photo of people, presumably medical staff, sitting in a circle and ...
Modbury Hospital
core   +1 more source

A Synchronization Condition for Coupled Nonlinear Systems with Time-delay -A Circle Criterion Approach-

, 2009
This paper considers the synchronization problem for coupled chaotic systems with time-delay. We assume that the error dynamics can be rewritten by a feedback connection of a linear delay system with multiple inputs and outputs and nonlinear elements ...
Nijmeijer, H., Oguchi, T., Tanaka, N.
core  

Circle of Willis-Guided Localization for Simultaneous Detection and Classification of Large Vessel Occlusions in Brain CTA. [PDF]

Neuroinformatics
Abramova V, Oliver A, Lal-Trehan Estrada UM, Hamadache RE, Martínez Arias P, Freixenet J, Terceño M, Silva Y, Lladó X.   +8 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source