Results 131 to 140 of about 17,391 (302)
BuildingsThe construction industry remains one of the main contributors to environmental degradation due to its high material consumption and massive waste generation.
Roberto Moya-Jiménez +6 more
doaj +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Circle radius distributions determine random close packing density [PDF]
Circles of a single size can pack together densely in a hexagonal lattice, but adding in size variety disrupts the order of those packings. We conduct simulations which generate dense random packings of circles with specified size distributions, and ...
Manuel, Julio Gabriel de Falco +3 more
core +2 more sources
A virtual visualization method for improving the manufacturing accuracy based VPP 3D printers
HeliyonCompared to traditional vat photopolymerization 3D printing methods, pixel blending technique provides greater freedom in terms of user-defined lighting sources.
Zhengdong Yu +7 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Gap Distributions in Circle Packings
, 2015 We determine the distribution of nearest neighbour spacings between the tangencies to a fixed circle in a class of circle packings generated by reflections. We use a combination of geometric tools and the theory of automorphic forms.
Rudnick, Z. (Zeév), Zhang, X. (Xin)
openaire +3 more sources
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
A Two-Stage Bin Packing Algorithm for Minimizing Machines and Operators in Cyclic Production Systems
AlgorithmsThis study presents a novel, two-stage algorithm that minimizes the number of machines and operators required to produce multiple product types repeatedly in cyclic scheduling. Our algorithm treats the problem of minimum machines as a bin packing problem
Yossi Hadad, Baruch Keren
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source