Results 111 to 120 of about 17,391 (302)
A Probability Collectives Approach with a Feasibility-Based Rule for Constrained Optimization
Applied Computational Intelligence and Soft Computing, 2011 This paper demonstrates an attempt to incorporate a simple and generic constraint handling technique to the Probability Collectives (PC) approach for solving constrained optimization problems.
Anand J. Kulkarni, K. Tai
doaj +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Budget visualizer using circle packing technique / Nursyahira Zulkeply [PDF]
, 2019 Data visualization is used to analyse the patterns and trends of data, including budget distributions, business analytics and so forth in a form of diagrams, charts and so on.
Zulkeply, Nursyahira
core
Circle packings and total geodesic curvatures in hyperbolic background geometry [PDF]
, 2023 In this paper, we study a new type of circle packings in hyperbolic background geometry. Horocycles and hypercycles are also considered in this packing. We give the existence and rigidity of this type of circle packing with conical singularities in terms
Sun, Yu, Hu, Guangming, Ba, Te
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Uniformizing Dessins And Belyi Maps Via Circle Packing [PDF]
, 1997 Grothendieck's theory of Dessins d'Enfants involves combinatorially determined affine, reflective, and conformal structures on compact surfaces. In this paper the authors establish the first general method for uniformizing these dessin surfaces
Kenneth Stephenson, Philip L. Bowers
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Hospital-Scale Chest X-Ray Database Visualization Using RAWGraph Technique [PDF]
Computer Science Journal of Moldova, 2020 For identification and screening of several lung diseases, the chest X-ray is just one of the very most often obtainable radiological tests. Most modern-day hospitals' Photo Archiving and Communication Systems (PACS) collect thousands of X-ray imaging ...
Haneen Hassan Al-Ahmadi
doaj
Rigidity of Infinite (Circle) Packings [PDF]
Journal of the American Mathematical Society, 1991 The following remarkable rigidity theorem for infinite circle packings is proved (the corresponding finite case is already known). Let T be an infinite, planar triangulation, and let Q be a circle packing on the sphere \(S^ 2\) with nerve T. Suppose that the union of all the circular discs of the packing and of the curved triangular regions in the ...
openaire +3 more sources
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source