Results 41 to 50 of about 15,767 (185)
Porcine Trypsin in the Manufacture of Biological Medicinal Products. Risks and Safety Requirements
Trypsin is a reagent widely used in the manufacture of biological medicinal products (BMPs). Until recently, pancreata of cattle, pigs and poultry were the main sources of trypsin preparations. The discovery of the disease called «transmissive spongiform
S. M. Sukhanov, E. M. Petruchuk
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ABSTRACT Background The global increase and fluctuations in high pathogenicity avian influenza (HPAI) cases and its impact on wild birds and poultry highlight the importance of serological surveillance. Serum is the standard sample material for antibody detection but obtaining serum from wild birds can be challenging. This study evaluated meat exudate (
Simone Kronborg +6 more
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Current advances in psittacine beak and feather disease: From molecular pathogenesis to integrated surveillance and global control strategies [PDF]
Background and Aim: Psittacine beak and feather disease (PBFD), caused by beak and feather disease virus (BFDV), is a globally distributed circoviral disease that threatens companion and captive psittacines, commercial aviculture, wildlife rehabilitation,
Hongmin Guan
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Current Understanding of the Pathogenesis of Porcine Circovirus 3
Circoviruses are closed, circular, single-stranded DNA viruses belonging to the family Circoviridae and the genus Circovirus. To date, at least four porcine circoviruses (PCVs) have been recognized, including PCV1 to PCV4, respectively.
Chaitawat Sirisereewan +2 more
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PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong +14 more
wiley +1 more source
A Rapid, Field‐Deployable Diagnostic Platform for Getah Virus Based on RT‐RAA and CRISPR EsCas13d
This study developed a rapid, one‐step, visual detection platform termed ROSVD by integrating RT‐RAA with CRISPR–EsCas13d, enabling simplified sample preparation, high‐sensitivity, on‐site detection of GETV within 30 min without the need for sophisticated equipment.
Liu Baoling +5 more
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Thanks to recent developments in molecular methods, many new species have been discovered within the genus Circovirus, which comprises viruses of veterinary relevance found in a broad range of hosts.
Matteo Legnardi +9 more
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Nucleolar protein NPM1 is essential for circovirus replication by binding to viral capsid
Entry of circovirus into the host cell nucleus is essential for viral replication during the early stage of infection. However, the mechanisms by which nucleolar shuttle proteins are used during viral replication is still not well understood.
Jianwei Zhou +9 more
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ABSTRACT Objective The aim of this study is to investigate the association between single nucleotide polymorphisms (SNPs) of porcine complement receptor 1‐like (CR1‐like) gene and its mRNA expression. Methods SNP identification, qRT‐PCR absolute quantification, linkage disequilibrium analysis and dual‐luciferase reporter assay were performed using 392 ...
Wei Yin +9 more
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ABSTRACT Xenotransplantation has entered a phase of accelerated clinical translation, necessitating renewed international consensus on governance, ethics, safety, and regulatory oversight. In September 2025, the International Xenotransplantation Association (IXA), in partnership with The Transplantation Society (TTS) and with engagement from the World ...
Wayne J. Hawthorne +25 more
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