Results 31 to 40 of about 22,658 (293)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Effectiveness of Guided Inquiry Based Laboratory Instruction on Prospective Science Teachers’ Procedural and Conceptual Understandings

open access: yesEducational Academic Research
The purpose of this study was to interrogate the effectiveness of open guided inquiry laboratory approach on prospective science teachers’ procedural and conceptual understanding of direct current circuits. The study was realized during the first year of
Ayşegül Sağlam Arslan   +1 more
doaj   +1 more source

Apprehending The Tour Operators Destination Brand Knowledge [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
The present study aims to understand and assess the tour operators destination brand knowledge of an Indian heritage tourism circuit the ‘Golden Triangle’. The concept has been measured utilizing Keller’s conceptual framework of the brand knowledge.
Dr. Kirti Singh Dahiya   +1 more
doaj  

Regulation of axon pathfinding by astroglia across genetic model organisms

open access: yesFrontiers in Cellular Neuroscience, 2023
Glia and neurons are intimately associated throughout bilaterian nervous systems, and were early proposed to interact for patterning circuit assembly. The investigations of circuit formation progressed from early hypotheses of intermediate guideposts and
Georgia Rapti   +2 more
doaj   +1 more source

Probing neural circuit mechanisms in Alzheimers disease using novel technologies. [PDF]

open access: yes, 2023
The study of Alzheimers Disease (AD) has traditionally focused on neuropathological mechanisms that has guided therapies that attenuate neuropathological features.
Xu, Xiangmin   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Relay vibration protection simulation experimental platform based on signal reconstruction of MATLAB software

open access: yesNonlinear Engineering, 2021
For conceptual analysis of the principle of relay vibration protection, this article establishes the simulation system model of directional current protection in MATLAB/Simulink environment through the protection algorithm.
Zhang Qian
doaj   +1 more source

Using stable isotopes to track hydrological processes at an oil sands mine, Alberta, Canada

open access: yesJournal of Hydrology: Regional Studies, 2022
Study region: This study was conducted at an oil sands operation in the Athabasca Oil Sands Region (AOSR), northeastern Alberta, Canada. The mine comprises open pit excavation of bituminous sands at two sites (Mildred Lake, ML, and Aurora North, AN ...
Spencer J. Chad   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Investigating student understanding of bipolar junction transistor circuits

open access: yesPhysical Review Physics Education Research, 2018
The research reported in this article represents a systematic, multiyear investigation of student understanding of the behavior of bipolar junction transistor circuits using a variety of different tasks to isolate and probe key aspects of transistor ...
Kevin L. Van De Bogart   +1 more
doaj   +1 more source

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