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This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Investigating student understanding of bipolar junction transistor circuits
The research reported in this article represents a systematic, multiyear investigation of student understanding of the behavior of bipolar junction transistor circuits using a variety of different tasks to isolate and probe key aspects of transistor ...
Kevin L. Van De Bogart +1 more
doaj +1 more source
Increasing Students’ Conceptual Understanding of AC Circuits: An Application of Licht’s Model [PDF]
Electrical and Computer Engineering DivisionTopic: “Increasing students’ conceptual understanding of AC circuits: An application of Licht’smodel”The complexity of AC circuit concepts warrants the use of an instructional method that presentsthe concept in an iterative manner such that students come to appreciate the nature of alternatingcurrent while ...
Nicole Pitterson, Ruth Streveler
openaire +2 more sources
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
The Bifurcation of Marxist Economic Analysis
Contemporary mainstream economics, in both its Keynesian and New Classicalist perspectives, failed to predict not only the eruption of the recent economic crisis circa 2007-08, but also the historically weak and uneven recovery of
Jack Rasmus
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Background A small minority of countries around the globe have podiatry as a recognized profession, hence, there are considerable differences among these countries when it comes to the curricula, the duration of training and legislation regulating the ...
Kevin Deschamps +5 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A Triangular Periodic Table of Elementary Circuit Elements [PDF]
Chua proposed an Elementary Circuit Element Quadrangle including the three classic elements (resistor, inductor, and capacitor) and his formulated, named memristor as the fourth element.
Wang, Frank Z.
core +1 more source
Semantic Grounding of Novel Spoken Words in the Primary Visual Cortex
Embodied theories of grounded semantics postulate that, when word meaning is first acquired, a link is established between symbol (word form) and corresponding semantic information present in modality-specific—including primary—sensorimotor cortices of ...
Max Garagnani +7 more
doaj +1 more source

