Results 51 to 60 of about 467,200 (296)

Circular and Elliptic Restricted Three Body Problems -A Comparison

open access: yes, 2021
The elliptic restricted three body problem has been well studied. However, the previous formulations of the problem have used a rotating coordinate system to keep the positions of the primary and secondary on the x-axis. This requires the rotation rate of the rotating coordinate system to speed up and slow down.
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

On the accuracy of the post-Newtonian approximation [PDF]

open access: yes, 2002
We apply standard post-Newtonian methods in general relativity to locate the innermost circular orbit (ICO) of irrotational and corotational binary black-hole systems.
Blanchet, Luc
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Pseudo-Newtonian planar circular restricted 3-body problem [PDF]

open access: yesPhysics Letters A, 2017
11 pages, 2 figures.
F.L. Dubeibe   +2 more
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Can We Create a Circular Pharmaceutical Supply Chain (CPSC) to Reduce Medicines Waste?

open access: yesPharmacy, 2020
Background: The increase in pharmaceutical waste medicines is a global phenomenon and financial burden. The Circular Economy, as a philosophy within the pharmaceutical supply chain, aims to promote waste reduction, maximise medicines value, and enable ...
Abdullah Alshemari   +3 more
doaj   +1 more source

Three-body orbital stability criteria for circular orbits [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1992
Previous investigations of the stability of hierarchical three-body systems by Harrington (1972, Cel. Mech., 1; 1975, AJ, 80 and 1977, AJ, 82), and by Black (1982, AJ, 87), Graziani & Black (1981, ApJ, 251) and Pendleton & Black (1983, AJ, 88) give conflicting results. A new numerical examination of such systems and the corresponding stability criteria
J. R. Donnison, D. F. Mikulskis
openaire   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

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