Results 61 to 70 of about 470,877 (338)

On the accuracy of the post-Newtonian approximation [PDF]

open access: yes, 2002
We apply standard post-Newtonian methods in general relativity to locate the innermost circular orbit (ICO) of irrotational and corotational binary black-hole systems.
Blanchet, Luc
core   +2 more sources

Three-body orbital stability criteria for circular orbits [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1992
Previous investigations of the stability of hierarchical three-body systems by Harrington (1972, Cel. Mech., 1; 1975, AJ, 80 and 1977, AJ, 82), and by Black (1982, AJ, 87), Graziani & Black (1981, ApJ, 251) and Pendleton & Black (1983, AJ, 88) give conflicting results. A new numerical examination of such systems and the corresponding stability criteria
J. R. Donnison, D. F. Mikulskis
openaire   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Circular 02/05 : quality and standards : reviewing performance : arrangements for colleges and other providers [PDF]

open access: yes, 2002
"This consultation circular is addressed to Learning and Skills Council (Council) funded colleges, Ufi hubs and other providers, including those delivering further education, work-based learning, adult and community learning, information, advice and ...

core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Construction of Analytical Eigensolutions for Isotropic Conical Bodies and Their Application for Estimation of Stresses Singularity

open access: yesFracture and Structural Integrity, 2019
A complete set of eigensolutions is constructed for different variants of circular conical bodies: homogeneous cone with one lateral surface (solid cone), homogeneous cone with two lateral surfaces (hollow cone) and composite cone for different variants ...
Tatyana Korepanova   +2 more
doaj   +3 more sources

Własności Mechaniczne Kilku Modeli Gruntów

open access: yesEngineering Transactions, 1964
This paper is devoted to the description and analysis of some results concerning problems of granular bodies representing continuous bodies. The test have been performed by means of samples composed of parallel glass rods of circular or polygonal cross ...
J. Biarez
doaj  

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