Results 51 to 60 of about 70,630 (259)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Własności Mechaniczne Kilku Modeli Gruntów
Engineering Transactions, 1964 This paper is devoted to the description and analysis of some results concerning problems of granular bodies representing continuous bodies. The test have been performed by means of samples composed of parallel glass rods of circular or polygonal cross ...
J. Biarez
doaj
Linear Polarization Variations and Circular Polarization Are Common among Airless Bodies
The Planetary Science JournalUsing the POLISH2 polarimeter at the Lick Observatory Shane 3 m and Nickel 1 m telescopes, we discover rotation-phase-locked variations in linear polarization to be common among asteroids and a near-Earth object (NEO) in a clear, 383−720 nm bandpass ...
Sloane J. Wiktorowicz +2 more
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CALCULATION OF THE VOLUME OF A CIRCULAR BODY
Thus, you will find that the method of using calculus to find volumes is far superior and has many more applications than the traditional geometry methods. With this in mind, we should understand the nature of variables and equations in terms of a 3D area. At this point, the important question to ask is: What is the volume of a volume?
Djumabayev, G'ulomjon +1 more
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Fracture and Structural Integrity, 2019 A complete set of eigensolutions is constructed for different variants of circular conical bodies: homogeneous cone with one lateral surface (solid cone), homogeneous cone with two lateral surfaces (hollow cone) and composite cone for different variants ...
Tatyana Korepanova +2 more
doaj +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source