Results 41 to 50 of about 6,300 (231)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

ARTISTIC MEANS OF REPRESENTING LOSS EXPERIENCE: M. MATIOS’ “MOMS” IN TRAUMA STUDIES CONTEXT [PDF]

Alfred Nobel University Journal of Philology
The article explores the latest work of the contemporary Ukrainian writer Maria Matios – “Moms”, in which the author continues the study of female trauma, which has remained overlooked by literary schol- ars until now.
Nataliya V. Maftyn, Serhii I. Cheripko
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Construction of sparse graphs with prescribed circular colorings

Discrete Mathematics, 2001
Suppose that \(G=(V,E)\) is a graph and \(k,d\) are positive integers with \(k\geq 2d\) and \((k,d)=1\). A \((k,d)\)-coloring of \(G\) is a mapping \(f:V\rightarrow \{0,1,\ldots, k-1\}\) such that for every edge \(xy\in E\), min\(\{|f(x)-f(y)|, k-|f(x)-f(y)|\}\geq d\). In this paper the following property is constructively proved: If \(k\geq 3d-2, (k,d)
Jaroslav Nesetril, Xuding Zhu
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Optimal on-line coloring of circular arc graphs [PDF]

RAIRO - Theoretical Informatics and Applications, 1995
Summary: We show that a certain optimal on-line coloring algorithm for interval graphs given independently by Kierstead and Ślusarek can be applied to a wider class of circular arc graphs. We prove that the competitive ratio of the algorithm is equal to 3 which improves a previous result by Marathe, Hunt and Ravi.
openaire   +2 more sources

Winding number and circular 4-coloring of signed graphs

CoRR, 2023
Concerning the recent notion of circular chromatic number of signed graphs, for each given integer $k$ we introduce two signed bipartite graphs, each on $2k^2-k+1$ vertices, having shortest negative cycle of length $2k$, and the circular chromatic number 4.
Anna Gujgiczer, Reza Naserasr, Rohini S, S. Taruni   +3 more
openaire   +2 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source