Results 91 to 100 of about 270,881 (261)

Sicilian Native Wool. From Waste to Resource

open access: yesDIID
This study focuses on Sicilian native wool, historically excluded from industrial supply chains due to its coarse morphology, and explores its regenerative potential across ecological, economic, and cultural dimensions.
Anna C. Catania, Carmen Trischitta
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Circular Product Practices for a Post-Plastic Transition

open access: yesDIID
The transition toward a post-plastic era challenges designers to develop strategies for the responsible use of polymeric materials within circular models.
Ludovica Rosato
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Circular Design Futures

open access: yesThe Design Journal, 2017
As The Design Journal celebrates its 20-year anniversary, the Textiles Environment Design (TED) research group at University of the Arts London marks a similar milestone moment. In this paper, I reflect on the journey I have taken as a member of this staff cluster of textile tutors and practicing industry designers.
openaire   +2 more sources

Circular Design in Design Education: A Case Study on the Use of Paper in Interior Design

open access: yesThe International Journal of Design Education, 2020
The article shows that the circular economy is more than just a new name for recycling: it is a systemic approach that involves circular use of resources. Understanding the latter is crucial for an industry like design, where as much as 80 percent of waste and the resultant pollution results from decisions taken in the design phase of the product.
openaire   +2 more sources

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Stone Circular Design and Material Regeneration

open access: yesDIID
This contribution aims to investigate the strategic role of design within the ecological transition and the circular economy, through an in-depth analysis of the STONE project.
Gabriele Pontillo   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy