Results 81 to 90 of about 270,881 (261)

Ecodesign Strategies for Battery Enclosures: A Design-Driven Approach to Modularity, Single-Materiality and Circularity

Designs
The environmental impact of battery systems is strongly influenced by early design decisions related to materials, structural architecture and assembly strategies.
Antoni Lara, Albert Cruz, Sylvia Andrea Cruz, Magnus Carl Fredrik Eriksson, Antonio Confalonieri, Andreu Sanz   +5 more
doaj   +1 more source

BIM and Circular Design

IOP Conference Series: Earth and Environmental Science, 2019
Materials passport is a tool to promote circular design. BIM is an essential and powerful tool to create and manage digital information. As such, it can be used for materials passports. Which information is needed and reliable? How can we extract it from a BIM model?
A Aguiar, R Vonk, F Kamp
openaire   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

An Approach for Idea Generation on Sustainable and Circular Products in the Early Phase Exemplified by a Vehicle Component

World Electric Vehicle Journal
Sustainability and circular economy are becoming increasingly important for new products due to new EU legislation and serve as orientation for product development.
Fabian Edel, Thomas Potinecke, Franziska Braun, Sebastian Stegmüller   +3 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Stimuli-responsive self-assembly and structural transition of a glycosylated triblock terpolymer: construction of “Sweet” nanoparticles

Materials & Design
Glycosylated nanoparticles, inspired by natural systems, hold great promise for biomedical applications such as targeted drug delivery and biosensing. However, achieving precise control over their self-assembly and responsiveness remains a challenge.
Mokun Chen, Marc C.A. Stuart, Vincent S.D. Voet, Rudy Folkersma, Katja Loos   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Modeling Land-Use Transitions under Conflicting Conservation and Land Tax Policies in Bang Kachao, Thailand

Environment and Natural Resources Journal
Bang Kachao Subdistrict faces a policy conflict between the 2019 conservation zoning regulation, which mandates at least 25% green cover, and the Land and Buildings Tax Act in 2019, which progressively increases idle land tax rates from 0.5% to 3% within
Sakol Teeravarunyou, Kochahem Kamolwit, Pongsak Kitirojpan, Pavinee Pattanachan, Jakkaphan Phatworaruthai, Sucheng Yao, Farbod Torabi   +6 more
doaj   +1 more source

Circular Design Strategies

, 2023
Le istanze della transizione verso gli obiettivi della Nuova strategia industriale europea richiedono un passaggio dalla logica della minimizzazione a quella di modelli rivolu- zionari di consumo e produzione che vanno oltre al concetto di sostenibilità.
Badalucco, L., Fortuna, P.
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source