Results 111 to 120 of about 14,077,311 (333)

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Going circular with what we wear and how we build: parallelisms between the Dutch and French catwalks of fashion and construction

Frontiers in Sustainability
Responding to the call for circular transition, the Dutch and French governments aspire to achieve a fully circular economy by developing a transitional agenda in various sectors, including fashion and construction. The two countries are among the top 10
Norman Dytianquin, Simon Paindavoine, Simon Paindavoine, Nikos Kalogeras, Nikos Kalogeras   +4 more
doaj   +1 more source

Golden spiral photonic crystal fiber: polarization and dispersion properties [PDF]

, 2008
A golden spiral photonic crystal fiber (GS-PCF) design is presented in which air holes are arranged in a spiral pattern governed by the golden ratio, where the design has been inspired by the optimal arrangement of seeds found in nature.
Antkowiak, Arti Agrawal, B. M. A. Rahman, Chen, Chen, Dudley, Fedotov, Hansen, J. Chen, K. T. V. Grattan, Kejalakshmy, N. Kejalakshmy, Shen, Steel, Suzuki, Yue, Zhang   +16 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

A fuselage/tank structure study for actively cooled hypersonic cruise vehicles, summary [PDF]

A detailed analytical study was made to investigate the effects of fuselage cross section (circular and elliptical) and the structural arrangement (integral and nonintegral tanks) on aircraft performance.
Baker, A. H., Pirrello, C. J., Stone, J. E.   +2 more
core   +1 more source

Product design and business model strategies for a circular economy

, 2016
The transition within business from a linear to a circular economy brings with it a range of practical challenges for companies. The following question is addressed: What are the product design and business model strategies for companies that want to ...
N. Bocken, I. de Pauw, C. Bakker, Bram van der Grinten   +3 more
semanticscholar   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Towards Circular Buildings in Hong Kong: A New Integrated Technology–Material–Design (TMD) Circularity Assessment Framework

Buildings
As Hong Kong faces increasing pressure on resources and environmental sustainability, there is a growing need to shift towards circular building practices.
Ericson K. S. Lau, Daniel W. M. Chan, Benjamin I. Oluleye, Timothy O. Olawumi   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source