Results 131 to 140 of about 99,515 (295)

Optical Nanosensor Architecture for Cell-Signaling Molecules Using DNA Aptamer-Coated Carbon Nanotubes

, 2011
We report a novel optical biosensor platform using near-infrared fluorescent single-walled carbon nanotubes (SWNTs) functionalized with target-recognizing aptamer DNA for noninvasively detecting cell-signaling molecules In real time.
Rickus, Jenna, Jong Hyun Choi, Choi, Jong Hyun, Sauffer, M. Dane, Benjamin A. Baker, Salgado, Janette, Jaroch, David, Janette Salgado, D. Marshall Porterfield, M. Dane Sauffer, David Jaroch, Jenna L. Rickus, Cha, Tae-Gon, Tae-Gon Cha, Baker, Benjamin A., Porterfield, D. Marshall   +15 more
core   +1 more source

Dynamic Regulation of Supramolecular Chirality in an Amphiphilic Dimeric Macrocycle Through Azobenzene‐Based Photoisomerization

Advanced Science, EarlyView.
A stimuli‐responsive supramolecular system has been rationally designed enabling hierarchical control over supramolecular handedness. This hybrid architecture retains orthogonal host‐guest properties and displays unique amphiphilicity‐directed chiral self‐assembly.
Minzan Zuo, Yi Shi, Xueqi Tian, Tao Zhang, Jianmin Jiao, Yuhong Shen, Yutong Xie, Jianwen Wei, Xiao‐Yu Hu   +8 more
wiley   +1 more source

Helicity-selective and spectrally tunable chiral thermal emissions

Nature Communications
Integrating nonlocal metasurfaces with thermal photonics has endowed thermal emissions with temporal and spatial coherence, as well as chirality. However, the static response of current thermal emitters hinders their broader applications, especially in ...
Kaili Sun, Haoye Qin, Mengqi Liu, Feng Chen, Yangjian Cai, Pinghui Wu, Cheng-Wei Qiu, Zhanghua Han   +7 more
doaj   +1 more source

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

Advanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander, Maria del Pilar Palacios Cisneros, Clara Certa, Megan Stierli, Katharina Beck, Nicolas Färber, Lisa Blank, Fiona Tanner, Eric Mühlberg, Sabrina Wohlfart, Christian Kleist, Jörg Huwyler, Gert Fricker, Walter Mier, Philipp Uhl   +14 more
wiley   +1 more source

Induced Circular Dichroism and Conformational Analysis of 2,2'-Binaphthyl Esters Derived from Primary Alcohols Prossessing a Stereogenic Center in the β-Position

, 2009
Circular dichroism calculations and conformational analyses of 2,2'-binaphthyl esters derived from primary alcohols with a chiral center in the β-position of the hydroxy group were performed using the time-dependent density functional theory(TD-DFT ...
TAKAHASHI, Ichiro, KATSUMOTO, Yukiteru, TANAKA, Takeyuki, SAKUSHIMA, Akiyo, HOSOI, Shinzo   +4 more
core  

Mechanism‐Informed Machine Learning Enables Discovery of Oncolytic Peptides for Cancer Immunotherapy

Advanced Science, EarlyView.
MISPOP integrates ensemble learning with membrane‐active physicochemical priors to identify Dermaseptin‐S9, a natural oncolytic peptide that disrupts tumor membranes, triggers immunogenic cell death, and shows strong antitumor activity. The study illustrates a mechanism‐informed route from peptide sequence data to cancer immunotherapy leads.
Wen Zhang, Shengxin Lu, Guangyong Zheng, Shensuo Li, Hongyu Chen, Mei Hong, Xiangru Zhou, Ruotian Tang, Ye Wu, Weidong Zhang, Dong Lu, Xin Luan   +11 more
wiley   +1 more source

Magnetic circular dichroism of Na3Nd(ODA)3.2NaClO4.6H2O

, 1996
This paper emphasizes the complementarity between optical and magneto-optical measurements on f elements. The magnetic circular dichroism, circular dichroism, and polarized absorption spectra of Na3Nd(ODA)3.2NaClO4.6H2O (NdODA), have been recorded at 4.2
Lambaerts, Hilde, H. Lambaerts, I. Couwenberg, M. F. Reid, C. Görller-Walrand, Reid, Michael F., Binnemans, Koen, Görller-Walrand, Christiane, L. Fluyt, K. Binnemans, Fluyt, Linda, Couwenberg, Ina   +11 more
core   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Continuum-electron interferometry for enhancement of photoelectron circular dichroism and measurement of bound, free, and mixed contributions to chiral response

Physical Review Research
We develop photoelectron interferometry based on laser-assisted extreme ultraviolet ionization for flexible and robust control of photoelectron circular dichroism in randomly oriented chiral molecules.
R. Esteban Goetz, Alexander Blech, Corbin Allison, Christiane P. Koch, Loren Greenman   +4 more
doaj   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source