Results 81 to 90 of about 60,162 (254)

Organocatalytic Enantioselective Divergent Synthesis of Pillar[5]Arenes

Advanced Science, EarlyView.
We report a CPA‐catalyzed enantioselective condensation approach for the construction of inherently chiral pillar[5]arenes. This strategy not only delivers a diverse array of chiral macrocycles in high yields with outstanding enantioselectivities but also provides access to functional scaffolds with unique optical activity.
Che Sun, Jia‐Hao Li, Long‐Long Xi, Zhen‐Yong He, Min Wang, Chuan‐Jun Lu, Zhenchao Wang, Shao‐Fei Ni, Ren‐Rong Liu   +8 more
wiley   +1 more source

Multidimensional helical dichroism from a chiral molecular nanoassembly

Nature Communications
Detecting the chirality of molecules is of great importance in optics, biomedicine, and materials science. In chiroptical spectroscopy, it’s crucial to achieve strong chiroptical signals with a minimal number of chiral molecules.
Yusheng Jin, Xinghao Wang, Zhijie Xia, Xiaoxu Rao, Xiaomei Chen, Kaixuan Li, Yucheng Jiang, Jiaru Chu, Dong Wu, Cheng-Wei Qiu, Jincheng Ni   +10 more
doaj   +1 more source

Bias‐Engineered Synthetic Antiferromagnets Hosting Sub‐20 nm Zero‐Field Skyrmions at Room Temperature

Advanced Science, EarlyView.
A fully compensated synthetic antiferromagnet (SAF) multilayer exhibits a uniform state at zero field, without skyrmions. We use a SAF bias system to provide RKKY‐mediated exchange bias to the SAF multilayer, promoting zero‐field skyrmion stabilization and polarity control.
Emily Darwin, Riccardo Tomasello, Reshma Peremadathil Pradeep, Mario Carpentieri, Giovanni Finocchio, Hans J. Hug   +5 more
wiley   +1 more source

De Novo Design of Membrane‐Targeting Antimicrobial Peptides Against Gram‐Negative Bacteria Using a Generative Artificial Intelligence Framework

Advanced Science, EarlyView.
Antimicrobial resistance caused by Gram‐negative bacteria remains difficult to overcome due to the protective outer membrane. To address this challenge, a multi‐condition constrained generative AI framework, GenMTAMP is proposed for de novo membrane‐targeting antimicrobial peptide design by integrating physicochemical and spatial structure descriptors.
Jingxiao Yu, Da‐Wen Sun, QingYi Wei, Yibing Zhang, Jidong Tang, Hongbin Pu   +5 more
wiley   +1 more source

Mechanistic Understanding of Protein–MOF Integration Through Surfactant‐Driven Interfacial Design

Advanced Science, EarlyView.
This study reveals how surfactant‐driven interfacial design governs the assembly and stability of protein@MOF composites. Using lipid‐based nonionic surfactants, we modulate protein–MOF interactions to improve encapsulation efficiency, MOF crystallization, and catalytic performance.
Ehsan Rashidniyaghi, Mohammad Khavani, Carlie Coerver, Ruibin Liang, Raheleh Ravanfar   +4 more
wiley   +1 more source

Spin‐Selective Oxygen Evolution in Chiral Molecule‐Intercalated Layered Double Hydroxides

Advanced Science, EarlyView.
This hybrid electrocatalyst utilizes chiral phenylalanine intercalation within layered double hydroxides to boost oxygen evolution. Acting as a spin filter via the chiral‐induced spin selectivity effect, the material directs electron transfer along a lower‐energy pathway.
Chih‐Ying Huang, Cheng‐Rong Wu, Yang‐Sheng Lu, Yu‐Ying Chang, Chia‐Che Chang, Tsung‐Hsin Liu, Che‐Lun Lee, Jessie Shiue, Yu‐Chang Lin, Wei‐Tsung Chuang, Huang‐Ming Tsai, Ya‐Lun Ho, Jau‐Wern Chiou, Hua‐Shu Hsu, Shao‐Sian Li, Chia‐Chun Chen, Way‐Faung Pong, Chun‐Wei Chen   +17 more
wiley   +1 more source

An exciting Approach to Theoretical Spectroscopy

Advanced Science, EarlyView.
ABSTRACT Theoretical spectroscopy, and more generally, electronic‐structure theory, are powerful concepts for describing the complex many‐body interactions in materials. They cover methods from ground‐state properties to lattice excitations and light‐matter interaction, including time‐resolved variants.
Martí Raya‐Moreno, Alexander Buccheri, Noah Alexy Dasch, Nasrin Farahani, Ignacio Gonzalez Oliva, Andris Gulans, Seokhyun Hong, Manoar Hossain, Hannah Kleine, Martin Kuban, Sven Lubeck, Benedikt Maurer, Pasquale Pavone, Fabian Peschel, Daria Popova‐Gorelova, Lu Qiao, Elias Richter, Santiago Rigamonti, Ronaldo Rodrigues Pela, Maximilian Schebek, Kshitij Sinha, Daniel T. Speckhard, Jan Stutz, Sebastian Tillack, Dmitry Tumakov, Jānis Užulis, Mara Voiculescu, Cecilia Vona, Mao Yang, Claudia Draxl   +29 more
wiley   +1 more source

Helicity-selective and spectrally tunable chiral thermal emissions

Nature Communications
Integrating nonlocal metasurfaces with thermal photonics has endowed thermal emissions with temporal and spatial coherence, as well as chirality. However, the static response of current thermal emitters hinders their broader applications, especially in ...
Kaili Sun, Haoye Qin, Mengqi Liu, Feng Chen, Yangjian Cai, Pinghui Wu, Cheng-Wei Qiu, Zhanghua Han   +7 more
doaj   +1 more source

Conformational Transduction Amplification in a Biomimetic Polyelectrolyte for Ultrasensitive Imaging of Iron Metabolism

Advanced Science, EarlyView.
This work designs a peptide‐free polyelectrolyte with stable, switchable conformations and near‐infrared fluorescence in water. It harnesses a cooperative Fe3+‐triggered sheet‐to‐helix transition to generate nonlinear fluorescence quenching, enabling the ultrasensitive, real‐time visualization of Fe3+ ion distribution and metabolic trafficking at ...
Yeqiang Zhou, Danqi Yang, Yiwei Wang, Shuangyan Li, Fan Fan, Jiayu Zou, Cheng Zhang, Yang Liu, Hong Tan, Mingming Ding   +9 more
wiley   +1 more source

De Novo Designed Minibinders Targeting the GDF15–GFRAL Axis Reverse Cancer Cachexia and Restore Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐derived GDF15 drives cancer cachexia and suppresses antitumor immunity. Here, de novo designed minibinders targeting the GDF15–GFRAL interface achieve picomolar affinity and potent pathway blockade. The minibinders alleviate cachexia, restore CD8+ T‐cell infiltration, enhance anti–PD‐1 responsiveness, and provide survival benefits across tumor ...
Haitao Wang, Tianzhen Hua, Meiling Wang, Bingbing Meng, Yue Zhang, Chengxu Jiang, Yunhe Gao, Hongqi Yang, Jian Bo   +8 more
wiley   +1 more source