Results 101 to 110 of about 1,315,460 (260)
International Journal of General MedicineFang Wang, Rui Liu, Cuirong Zhang, Shenglin Liu Department of Cardiology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200120, People’s Republic of ChinaCorrespondence: Shenglin Liu, Email isl0076@163.comObjective: To ...
Wang F, Liu R, Zhang C, Liu S
doaj
Circular at the very beginning: on the initial genomes in the RNA world
RNA BiologyIt is likely that an RNA world existed in early life, when RNA played both the roles of the genome and functional molecules, thereby undergoing Darwinian evolution.
Yufan Luo +3 more
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Circular on Development of the Medium-Term Revenue Strategy (MTRS) for FY 2023/2024-2026-2027
, 2022 The purpose of this Circular is to inform the Government Ministries, Departments and Agencies (MDAs) and the County Governments of the Government's intention to develop a Strategy to enhance revenue mobilization to facilitate implementation of Government
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Circular on Guidelines for Development and Review of Human Resource Management Instruments for State Corporations and Public Universities [PDF]
, 2023 Reference is made to the Public Service Commission Circular Letter Ref. No. PSC/GEN/22/11/(18) dated 12th June, 2023 vide which the Commission requested for stakeholder views on the draft Guidelines for Development and Review of Human Resource Management
The Public Service Commission
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Circular RNA in hepatocellular carcinoma: emerging therapeutic strategies
Frontiers in ImmunologyCircular RNAs, or circRNAs, are unique single-stranded RNA molecules that form covalently closed circles. They possess a wide range of cellular functions and can act as tumor suppressors or promoters, regulating various aspects of carcinogenesis.
Gregor Jazbec, Tadeja Režen
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Determination of ribonuclease sequence-specificity using Pentaprobes and mass spectrometry
, 2012 The VapBC toxin-antitoxin (TA) family is the largest of nine identified TA families. The toxin, VapC, is a metal-dependent ribonuclease that is inhibited by its cognate antitoxin, VapB. Although the VapBCs are the largest TA family, little is known about
Cook, Gregory M. +13 more
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Identification of novel components of Trypanosoma brucei editosomes [PDF]
, 2003 The editosome is a multiprotein complex that catalyzes the insertion and deletion of uridylates that occurs during RNA editing in trypanosomatids. We report the identification of nine novel editosome proteins in Trypanosoma brucei.
Schnaufer, Achim; id_orcid +6 more
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, 2023 Circular RNAs (circRNAs), a newly recognized group of noncoding RNA transcripts, have established widespread attention due to their regulatory role in cell signaling. They are covalently closed noncoding RNAs that form a loop, and are typically generated
1000050242110 +17 more
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source