Results 41 to 50 of about 180,157 (288)

Las normas administrativas y el sistema de fuentes Administrative Norms and the Sources of Law System

open access: yesRevista de Derecho (Coquimbo), 2010
En esta investigación se analiza, desde una perspectiva general, la naturaleza, fundamentos y efectos de las diversas normas que emanan de los órganos de la Administración del Estado, con el objeto de establecer un marco general para comprender la forma ...
Eduardo Cordero Quinzacara
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Cubiertas autoportantes circulares aplicando el método de elementos finitos

open access: yesGaceta Técnica, 2022
Las naves industriales constituyen estructuras destinadas a varios usos en el comercio o desarrollo de una determinada población, en consecuencia, este tipo de estructuras son muy demandadas en el campo de la ingeniería civil, sobre todo en el área de ...
Cristhian Daniel Páez Redrován   +1 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Comparación morfométrica entre lagunas de la planicie aluvial del río Paraná Medio y La Lomada Norte (Corrientes, Argentina)

open access: yesCuadernos de Geografía: Revista Colombiana de Geografía, 2015
El desarrollo de la linea de costa (DL ) es una medida morfométrica que permite conocer cuantitativamente la forma de la cubeta. El objetivo de este trabajo es comparar el DL de un grupo de lagunas que, aunque se encuentran en una misma región, son ...
Félix Ignacio Contreras   +1 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Soporte jurídico de las depuraciones [PDF]

open access: yes, 2009
Este trabajo se centra en la historia del derecho y consiste en analizar el soporte jurídico de las depuraciones franquistas, intentando exponer de manera clara las leyes y órdenes que se dictaron.
Blasco Gil, Yolanda
core  

Definitions of the circular economy: Circularity matters

open access: yesEcological Economics, 2023
With more than 4,000 research articles in 2022 the Circular Economy is clearly a topic that meets academic interest. With resource use at an all-time, unsustainable peak it is also a topic that raises great expectations: We need the circular economy. The great hopes that we all have are further fueled by the definitions of the circular economy that we ...
Figge, Frank   +2 more
openaire   +2 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard   +5 more
wiley   +1 more source

Formación de redes dirigidas circulares con costos de enlace compartidos

open access: yesEstudios Económicos, 2003
Formación de redes dirigidas circulares con costos de enlace ...
Juan Manuel Larrosa, Fernando Tohmé
doaj   +2 more sources

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