Results 41 to 50 of about 1,211 (263)
El desarrollo de la linea de costa (DL ) es una medida morfométrica que permite conocer cuantitativamente la forma de la cubeta. El objetivo de este trabajo es comparar el DL de un grupo de lagunas que, aunque se encuentran en una misma región, son ...
Félix Ignacio Contreras +1 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Formación de redes dirigidas circulares con costos de enlace compartidos
Formación de redes dirigidas circulares con costos de enlace ...
Juan Manuel Larrosa, Fernando Tohmé
doaj +2 more sources
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Cobrança de tributos extra-orçamentários — A fôrça das circulares fazendárias — O pagamento do imposto — O fato gerador do imposto — Imposto e alíquota.
Alberto Deodato
doaj +4 more sources
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
É apresentado o estudo de amostras circulares de 0,636 km² de redes de drenagem dos solos do Parque Estadual da Serra do Mar - Núcleo Cunha (S .Paulo, Brasil).[...]
Ana Maria Conte +3 more
doaj +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A DANÇA COMO ESTRATÉGIA DE AUTOCUIDADO PROFISSIONAL EM CUIDADOS PALIATIVOS
O investimento no autocuidado é fundamental para alcançar uma harmonia saudável entre a vida pessoal e profissional dos profissionais da área dos cuidados paliativos.
Deolinda Leão, Carla Ribeirinho
doaj +1 more source

